Restless legs syndrome

M Manconi, D Garcia-Borreguero… - Nature reviews Disease …, 2021 - nature.com
The primary pathology of restless legs syndrome (RLS) may relate to brain iron deficiency
that might induce hyperdopaminergic and hyperglutamatergic states. Such interplay between …

The management of restless legs syndrome: an updated algorithm

MH Silber, MJ Buchfuhrer, CJ Earley, BB Koo… - Mayo Clinic …, 2021 - Elsevier
Restless legs syndrome (RLS) is characterized by an urge to move the legs, usually in …
responsible use for refractory restless legs have been developed 17 ; the use of intravenous iron …

[HTML][HTML] Restless legs syndrome: contemporary diagnosis and treatment

TR Gossard, LM Trotti, A Videnovic, EK St Louis - Neurotherapeutics, 2021 - Elsevier
The severity of impairment from RLS is commonly measured subjectively by rating scales
such as the International Restless Legs Syndrome Study Group rating scale (IRLS) or its self-…

New insights into the neurobiology of restless legs syndrome

S Ferré, D García-Borreguero, RP Allen… - The …, 2019 - journals.sagepub.com
the enhancer activity of an restless legs syndrome (RLS)–risk common polymorphism of the
regulatory locus of the gene MEIS1 in the … embryos after injection of the protective (left, “A” for …

Update on restless legs syndrome: from mechanisms to treatment

P Gonzalez-Latapi, R Malkani - Current neurology and neuroscience …, 2019 - Springer
… of the molecular pathways and recent genetic risk loci associated with restless legs syndrome/…
Karl Axel Ekbom coined the term “restless legs syndrome” and described all the clinical …

Exploration of restless legs syndrome under the new concept: A review

Z Liu, R Guan, L Pan - Medicine, 2022 - journals.lww.com
Restless leg syndrome (Restless legs syndrome, RLS) is a common neurological disorder.
The … recent pathophysiological developments have shown the contribution of various genetic …

Restless legs syndrome: An overview of pathophysiology, comorbidities and therapeutic approaches

A Vlasie, SC Trifu, C Lupuleac… - Experimental and …, 2022 - spandidos-publications.com
… pathophysiology, common comorbidities and current therapeutic modalities in the
treatment/management of restless legs syndrome (RLS) a sensorimotor neurological disorder. …

Restless legs syndrome: known knowns and known unknowns

E Antelmi, L Rocchi, A Latorre, D Belvisi, F Magrinelli… - Brain Sciences, 2022 - mdpi.com
Restless legs syndrome (RLS) is a common neurological disorder affecting up to 15% of the
general population [1,2,3]. It is categorized as a sleep-related movement disorder (MD) due …

Why are women prone to restless legs syndrome?

MV Seeman - International journal of environmental research and …, 2020 - mdpi.com
… in the evening and at night and (b) uncomfortable sensations in the legs that are relieved by
movement. RLS is diagnosed according to the International Restless Legs Syndrome Study …

Pharmacologic treatment of restless legs syndrome

Q Lv, X Wang, T Asakawa… - Current …, 2021 - ingentaconnect.com
… A report from the restless legs syndrome diagnosis and epidemiology workshop at …
Cabergoline compared to levodopa in the treatment of patients with severe restless legs syndrome: …