… Osteoporosis (OP) is another systemic skeletal disease … Recent studies have shown that
osteopontin (OPN) plays a vital role in … This review summarizes the role of OPN in regulating …

… Sarcopenia, osteoporosis and osteoarthritis are typical diseases associated with … body’s
defense response to neurodegeneration with the role of eliminating pathogenic Aβ. At present, …

… Multiple sclerosis (MS) which shows both neuroinflammatory … as osteocalcin (OCN),
osteopontin (OPN), and fibroblast … a vital role in bone loss of ovariectomized osteoporosis mouse …

… potential treatment options in the future. In this review, we attempt to address the role of …
OPN neutralization by 23C3 improves arthritis and osteoporosis [208]. A humanized version of …

… shared etiologic (vitamin D deficiency and smoking) and pathogenic factors (cytokines,
osteopontin… for MS itself, thereby illustrating one of the shared pathways in OP and MS [135]. Low …

… ) contains multiple cells that play a crucial role in cancer pathogenesis. There are … multiple
sclerosis models, OPN increases phosphorylation of IKKβ and activation of the NF-κB pathway …

… bone and allergy that share pathways, cells, cytokines and … activator of bone resorption
process is osteopontin (OPN), an … , such as rheumatoid arthritis, multiple sclerosis, psoriasis [47], …

… Psoriasis (Ps) is a chronic inflammatory skin disease of complex pathogenesis with genetic
… postmenopausal women and may be associated with bone loss and osteoporosis [20,21]. …

… -I, osteocalcin, and osteopontin, as … multiple therapeutic targets for further study. Therefore,
we hope our review is also helpful in the development of osteoporosis research and treatment…

… and characterize its role in diabetes mellitus, osteoporosis, … in the management and treatment
of aforementioned diseases. In … status in postmenopausal osteoporosis, osteoarthritis and …