[HTML][HTML] Apoptosis (programmed cell death) and its signals-A review

E Obeng - Brazilian Journal of Biology, 2020 - SciELO Brasil
Apoptosis is a process of sequential order of cell death thus referred to as a programmed
cell death that first emerge in … P53 is a tumor suppressor protein existing as a tetramer with …

[HTML][HTML] Programmed cell death detection methods: a systematic review and a categorical comparison

S Kari, K Subramanian, IA Altomonte, A Murugesan… - Apoptosis, 2022 - Springer
… different types of programmed cell death make it challenging to … of different forms of
programmed cell death along with their … p53 mutation and inhibition of apoptosis also cause …

The multiple mechanisms that regulate p53 activity and cell fate

A Hafner, ML Bulyk, A Jambhekar… - … reviews Molecular cell …, 2019 - nature.com
… on cell type. How p53 integrates these and other cues to choose between the competing
cell survival and cell death outcomes has been of great interest and is still largely unknown. …

Emerging connectivity of programmed cell death pathways and its physiological implications

S Bedoui, MJ Herold, A Strasser - Nature reviews Molecular cell biology, 2020 - nature.com
cells is driven by programmed cell death (PCD) pathways, highlighting their important roles
in … by the tumour suppressor p53 — may sensitize malignant cells to the ligands of these …

[HTML][HTML] Progress in understanding the role of lncRNA in programmed cell death

N Jiang, X Zhang, X Gu, X Li, L Shang - Cell death discovery, 2021 - nature.com
… Regulation of the p53 tumor suppressor pathway … p53-related lncRNA P53RRA can directly
interact with the functional domain of the signal protein in the cytoplasm by activating the p53

Programmed cell death pathways in hearing loss: A review of apoptosis, autophagy and programmed necrosis

J Wu, J Ye, W Kong, S Zhang, Y Zheng - Cell proliferation, 2020 - Wiley Online Library
Apoptosis is an active and highly ordered cell death process regulated by genes (including
Bcl-2, p53 and c-Jun) and a series of enzymes (including caspases and endonuclease G (…

The regulatory roles of p53 in cardiovascular health and disease

H Men, H Cai, Q Cheng, W Zhou, X Wang… - Cellular and Molecular …, 2021 - Springer
… In pathological cardiovascular circumstances, p53 expression is elevated … p53 plays a
regulatory role via anti-angiogenesis, pro-programmed cell death, metabolism regulation, and cell

Ferroptosis–An iron-and disorder-dependent programmed cell death

MB Djulbegovic, VN Uversky - International journal of biological …, 2019 - Elsevier
… Of all the proteins examined in this study, the highest level of disorder content of [0.6,0.7)
was found in tumor protein 53 (p53), for which the crucial importance of intrinsic disorder for …

[HTML][HTML] Apoptosis, autophagy, NETosis, necroptosis, and pyroptosis mediated programmed cell death as targets for innovative therapy in rheumatoid arthritis

J Zhao, P Jiang, S Guo, SJ Schrodi, D He - Frontiers in immunology, 2021 - frontiersin.org
… Interestingly, geldanamycin (GA) can promote ROS production in RA associated FLS and
induce apoptosis in vitro (48). In addition, programmed cell death 5 (PDCD5) and P53 may …

[HTML][HTML] The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases

M Li - Apoptosis, 2021 - Springer
… PUMA has been found to play a critical role in ovarian apoptosis. In the … of programmed
cell death and describe recent updates to the understanding of both P53-dependent and P53-…