… Uterine leiomyomas (ULs) are the most common benign smooth muscle cell steroid-dependent
tumors that occur in women of reproductive age. Progesterone (… its nuclear progesterone …

… We showed that both nuclear and membrane progesterone receptors were relevant in
the treatment of uterine leiomyomas, especially when combined with selective progesterone …

… signaling has been shown to mediate a regulatory function in uterine development associated
with progesterone signaling … in responsiveness to progesterone signaling in female mice […

… role progesterone plays in UF pathogenesis [32]. In this article, we reviewed the literature
covering progesterone signaling in UF pathogenesis … via modulation of progesterone signaling, …

… in the uterus, progesterone (P4) also play a key role in UF … There are conflicting results about
the role of progesterone in … the essential role of the progesterone in the pathogenesis of UFs…

… to human uterine leiomyomas, including altered estrogen and progesterone receptor pathways.
… mechanism for the aberrant function of progesterone receptor in uterine leiomyomas. …

… of progesterone on uterine leiomyoma cell growth. We found that progesterone acts on primary
cultures of uterine leiomyoma … inhibiting the apoptosis of leiomyoma cells. Increased Ki67 …

… We review recent studies dealing with the molecular genetics and basic results of omics
analysis of uterine leiomyoma (LM)—a common benign muscle tumor of the uterus. Whole …

… Traditionally, estrogen has been considered as the major promoter of leiomyoma growth.
However, in recent years, the role of progesterone in the pathogenesis of leiomyomas has …

… by the age of 50 is >80% for African-American women and ~70% for Caucasians, suggesting
that African-American women show a higher risk of developing uterine leiomyoma [170]. In …