… and verapamil to evaluate their potentiating capacity. … drugs in preclinical models [19,20].
Its capacity to inhibit … at which the time-kill kinetics assays were performed (Section 2.6.). On …

… In this study, we evaluate the effect of … the time-kill kinetics of the two drugs alone and
in combination against M. bovis BCG strain. Kill kinetics is an important asset of the pre-clinical …

… The role of the time-kill kinetics assay as part of a preclinical modeling framework for
assessing the activity of anti-tuberculosis drugs. Tuberculosis. 2017;105:80–5. …

… A study for the investigation of the importance of an in vitro time kill-kinetics assay as an …
preclinical modeling framework evaluating the activity of anti-tuberculosis drugs used this assay. …

… Here, we discuss key in vitro and in vivo preclinical models that can … framework to evaluate
HDTs for Mtb infection, (1) drug PK … Anti-tuberculosis effect of isoniazid scales accurately from …

… a promising novel class of anti-tuberculosis agents. One such … initial screening of anti-TB
agents in preclinical development. … vitro time-kill experiments and its anti-mycobacterial activity …

… The role of the time-kill kinetics assay as part of a preclinical modeling framework for
assessing the activity of anti-tuberculosis drugs. Tuberculosis (Edinb). 2017;105:80-5. …

… Finally, the lack of amikacin modifying activity in M. avium is … However, our time-kill kinetic
results show that berberine is … Funding: This work was supported in part by a personal grant …

… To evaluate the robustness of the inhibitory effect of the ZnO … Time-kill kinetics was evaluated
for the ZnO NPs and RIF alone, and … activity, which results in the loss of cell viability. (44,45)…

… in toxicology studies during preclinical development. However, it … in whole-cell assays to
evaluate their activity against the … tuberculosis, or in time-kill curves to have their mechanism of …