Extended access self-administration of methamphetamine is associated with age-and sex-dependent differences in drug taking behavior and recognition memory in …

SR Westbrook, MR Dwyer, LR Cortes… - Behavioural brain …, 2020 - Elsevier
… a methamphetamine (METH) self-administration paradigm to investigate the … fashion.
To this end, we trained Sprague-Dawley rats of both sexes to self-administer METH or a non-drug

Translating human drug use patterns into rat models: exploring interindividual differences via refined drug self-administration procedures

G D'Ottavio - 2024 - iris.uniroma1.it
… I will also provide an overview of the various drug self-administration procedures that were …
animal models of drug self-administration along with the more recent incorporation of drug-vs-…

Opposite regulation of conditioned place preference and intravenous drug self-administration in rodent models: Motivational and non-motivational examples

TA Green, MT Bardo - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
… haloperidol) of the drug of abuse will decrease the “apparent” dose of the drug of abuse and
… to the right in all three models (CPP, FR- and PR--SA) in a similar parallel fashion (Fig. 1). …

Animal models of drug relapse and craving after voluntary abstinence: a review

I Fredriksson, M Venniro, DJ Reiner, JJ Chow… - Pharmacological …, 2021 - ASPET
… recently developed animal models of drug relapse and craving … consequences to ongoing
drug self-administration or by … models are different from the classic models in which drug is …

The active heroin metabolite 6-acetylmorphine has robust reinforcing effects as assessed by self-administration in the rat

R Avvisati, IL Bogen, JM Andersen, V Vindenes… - …, 2019 - Elsevier
… The post-hoc tests showed that priming with both drugs reestablished self-administration
in the saline pretreated animals, but in the animals pretreated with the 6-AM mAb only the …

Studying sex differences in rodent models of addictive behavior

AK Radke, EA Sneddon, SC Monroe - Current Protocols, 2021 - Wiley Online Library
… Female rodents are more likely to acquire drug self-administration behaviors, consume … of
self-administration models, a broad view of female versus male self-administration behaviors, …

[PDF][PDF] Morinda citrifolia Linn.(Noni) fruit extract attenuates ethanol seeking behavior in mouse runway paradigm

Y Khan, V Pandy - J Res Pharm, 2020 - researchgate.net
… Recently, we developed a novel runway model of drug selfadministration using mice without
compromising a great active long-term analysis of runway efficient performance for drug

Drug Addiction and Drug Dependency

DR Maguire - Drug Discovery and Evaluation: Safety and …, 2022 - Springer
Drug selfadministration procedures have very high predictive validity … drug self-administration
training. Pretraining with food is not required, however, as selfadministration of many drugs

Animal models of addiction

EL Gardner - Textbook of Addiction Treatment: International …, 2021 - Springer
… For example, the workload may increase in a steeply incremental fashion: one lever press
… the extended access animal drug self-administration model yielding important insights into …

Hold-down as an alternative to unit dose in cocaine self-administration experiments: Characterization using a progressive ratio schedule

DCS Roberts, BA Zimmer - Psychopharmacology, 2020 - Springer
… publications involving IV drug self-administration in rodents and … IV self-administration
experiment makes no consummatory response; instead, the subject is a passive recipient of a drug