Innate lymphoid cells in intestinal homeostasis and inflammatory bowel disease

A Saez, R Gomez-Bris, B Herrero-Fernandez… - International Journal of …, 2021 - mdpi.com
… Recent studies of intestinal mucosal homeostasis and IBD suggest involvement of innate
lymphoid cells (ILCs). These lymphoid-origin cells are innate counterparts of T cells but lack the …

[PDF][PDF] Characterization of transcriptional regulatory networks that promote and restrict identities and functions of intestinal innate lymphoid cells

M Pokrovskii, JA Hall, DE Ochayon, R Yi… - Immunity, 2019 - cell.com
Innate lymphoid cells contribute to tissue homeostasis and defense against pathogens, …
genome-scale transcriptional regulatory network describing how intestinal ILC gene expression …

[HTML][HTML] Tissue-specific features of innate lymphoid cells

I Meininger, A Carrasco, A Rao, T Soini, E Kokkinou… - Trends in …, 2020 - cell.com
… Recent progress in the characterization of innate lymphoid cells (ILCs) across various organs
… The spectrum and regulatory landscape of intestinal innate lymphoid cells are shaped by …

Subsets of ILC3− ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues

M Cella, R Gamini, C Sécca, PL Collins, S Zhao… - Nature …, 2019 - nature.com
… gene expression by changing the chromatin landscape via deacetylation of local histones
… Control patients for the present study were patients undergoing abdominal surgery for colon

Innate lymphoid cells control signaling circuits to regulate tissue-specific immunity

CSN Klose, D Artis - Cell research, 2020 - nature.com
… to LTi cells and are therefore referred to as LTi-like lymphocytes. In the intestine, they are …
Consequently, dietary metabolites can shape the immune responses via regulation of ILC2s …

Dynamic regulation of innate lymphoid cells in the mucosal immune system

F Shao, D Yu, P Xia, S Wang - Cellular & molecular immunology, 2021 - nature.com
… For the migration of ILC1s to the intestine, migration is … receptors are regulated by mucosal
dendritic cells and the gut-… among immune cells within the inflammatory environment. For …

Innate lymphoid cells and intestinal inflammatory disorders

M Zheng, J Zhu - International Journal of Molecular Sciences, 2022 - mdpi.com
cells that do not express T cell or B cell antigen-specific … Type 1 innate lymphoid cells (ILC1s)
are defined by the … the roles of gut-resident ILCs shaped by the gut environment, …

Group 3 innate lymphoid cells in intestinal health and disease

V Horn, GF Sonnenberg - Nature Reviews Gastroenterology & …, 2024 - nature.com
… The latest studies provide new insights into the mechanisms by which ILC3s fundamentally
shape intestinal homeostasis or disease pathophysiology, and often this functional …

Innate lymphoid cells and gastrointestinal disease

Z Wang, J Wang - Journal of Genetics and Genomics, 2021 - Elsevier
… ILCs also play an important role in maintaining the homeostasis of the body, particularly
in the complex and diverse environment of the intestine. ILCs respond to different …

[HTML][HTML] The interplay between innate lymphoid cells and T cells

M Cherrier, G Ramachandran, R Golub - Mucosal Immunology, 2020 - Elsevier
shape T-cell responses is strongly dependent on the tissue and inflammatory context. Likewise,
indirect regulation … of gut associated tertiary lymphoid structures and in intestinal NCR1 + …