The transition to compulsion in addiction

C Lüscher, TW Robbins, BJ Everitt - Nature Reviews Neuroscience, 2020 - nature.com
loss of control over drug taking (Box 1) and the transition to compulsive drug taking or
compulsive drug … mechanism of cue-associated seeking and locomotor sensitization 24,62 . Daily …

[HTML][HTML] Cued for risk: Evidence for an incentive sensitization framework to explain the interplay between stress and anxiety, substance abuse, and reward uncertainty …

SN Hellberg, TI Russell, MJF Robinson - Cognitive, Affective, & Behavioral …, 2019 - Springer
compulsive drug use and relapse. Notably, evidence for … Substantial financial losses
are often accompanied by poor … cases repeated drug use results in no change in drug “liking,” …

[HTML][HTML] … and incentive-sensitization perspective on compulsive use of social networking sites–wanting but not liking predicts checking frequency and problematic use …

N Ihssen, M Wadsley - Addictive Behaviors, 2021 - Elsevier
… the drug addiction literature that focus on incentive processes (incentive-sensitization and …
experimental measures with tightly controlled stimuli (eg control logos) and compare ‘baseline…

Compulsive alcohol seeking results from a failure to disengage dorsolateral striatal control over behavior

C Giuliano, D Belin, BJ Everitt - Journal of Neuroscience, 2019 - Soc Neuroscience
… the course of drug exposure the control over drug seeking … of aDLS in the switch from
controlled to compulsive drug use in … I rats thereby accounts for the lack of a relationship between …

[HTML][HTML] How to pin a compulsive behavior down: A systematic review and conceptual synthesis of compulsivity-sensitive items in measures of behavioral addiction

I Muela, JF Navas, JM Ventura-Lucena, JC Perales - Addictive behaviors, 2022 - Elsevier
… frequently included in non-substance addiction scales (eg, “… (along with craving) from
incentive sensitization, whereas the … questions about time lost, distress, loss of control, functional …

Neurobiology of cue-reactivity, craving, and inhibitory control in non-substance addictive behaviors

S Antons, M Brand, MN Potenza - Journal of the Neurological Sciences, 2020 - Elsevier
… the sensitization of the mesocorticolimbic dopamine system (reward network) as a result of
repeated drug use. … , leading to compulsive drug intake. Similarly, within the neurocircuitry of …

Neural substrates and circuits of drug addiction

MW Feltenstein, RE See… - … in medicine, 2021 - perspectivesinmedicine.cshlp.org
Drug addiction is a chronic relapsing disorder, and a … development, loss of control, and
persistence of compulsive addictive … the transition from casual drug use to the loss of control and …

[HTML][HTML] The transition to cocaine addiction: the importance of pharmacokinetics for preclinical models

AB Kawa, F Allain, TE Robinson, AN Samaha - Psychopharmacology, 2019 - Springer
… changes, and drug use would remain under control, at least … to study the transition to
compulsive-like drug seeking behavior… sensitization, incentive-sensitization, dopamine …

[HTML][HTML] Intermittent but not continuous access to cocaine produces individual variability in addiction susceptibility in rats

AF Garcia, IG Webb, LM Yager, MB Seo… - …, 2020 - Springer
drug use, robust locomotor sensitization, and high levels of … why some drug users transition
to addiction and others do not. … compulsive drug-taking and drug-seeking, loss of control over …

Value, drug addiction and the brain

K Loganathan, ETW Ho - Addictive behaviors, 2021 - Elsevier
moving to brain-wide networks involved in valuation, control … to the habit and compulsion
theories of addiction, the decision… Repeated drug use may sensitize the brain’s dopaminergic …