… is compulsive drug seeking and drug taking despite severe harms and an inability to control
the strong urges to consume the drug, … in NAc and behavioral sensitization to cocaine (82), …

… In some individuals, substance use disorder (SUD) may worsen … transition from goal-directed
behavior to loss of control and compulsive-like drug seeking in addiction involves a shift …

… from flexible decision making to compulsive drug seeking (… by the fact that we controlled for
baseline substance use and the … suggests that sensitization to substance-related cues, along …

… inadvertently focused on regulated food or drug consumption that is … over consumption, and
compulsive patterns of intake. … The transition from controlled to dysregulated drug and food …

… from the National Institute on Drug Abuse (NIDA) breeding … and control groups from 260 to
300 pA (p < 0.05, controlled … perpetuation of compulsive opioid seeking and taking. Consistent …

… Compulsive eating is partly defined by “loss of control” in the … the transition from casual
to compulsive substance use. The “… of addiction proposes that substances of abuse initially …

… participants exhibited evidence of greater attentional control by reward-signaling stimuli. …
exposure to addiction-related behaviors and/or substance use having sensitized incentive …

… essence of addiction: compulsive drug seeking and use, even in … -sensitization changes in
addicts make drug use especially … The ability of an addict to control drug use, even in the short …

… by a compulsive and chronically relapsing pattern of drug use, … (salience attribution change)
of drug and drug-related cues.… Loss of control over drug use is a key feature of addiction.…

… Rats were housed in pairs in standard controlled environmental … of behavioral sensitization
in adulthood and no change in … Since either phenotype could exhibit drug abuse liability, we …