… Certain aspects of control over drug use are clearly reduced, … in addiction science that can
move the field forward. … that usually signifies some lack of ability to control one's behavior, and …

… sensitize with repeated drug exposure and withdrawal and drive an increase in the role of
negative reinforcement in maintaining substance use as addiction … control that are associated …

… to drugs or drug cues is associated with a “sensitization” or … networks can be linked to a shift
in incentive salience, with … reliably differentiate drug users from healthy control participants …

… on stress induced sensitization of insula activation predicts … from controlled substance use
to compulsive drug taking. … only the loss but also the regaining of control over drug use in …

… control, whereas the strong desire for drugs might be explained by a neurocomputational
model of incentive sensitization … from goal-directed to habitual and ultimately compulsive drug-…

… Rats were housed in pairs in standard controlled environmental … of behavioral sensitization
in adulthood and no change in … Since either phenotype could exhibit drug abuse liability, we …

… the shift from controlled to compulsive alcohol seeking and … ] and sensitization of the mesolimbic
DA pathway to drugs or … act in synergy to drive compulsive drug use. Indeed, through the …

… to compulsion, and that this tendency is under the control of … in rewarding behaviours, including
drug addiction, appears to … from sensitization, promotes a more rapid switch from flexible …

… reverse tolerance (or drug sensitization) thus exhibiting a … tolerance to drugs used for
depression and related phenomena. … naturalistic studies, rather than on controlled trials. In …

… and substance use disorders. … by the SIP procedure [52], has been associated with an
increased vulnerability to switch from controlled to compulsive alcohol use, a key feature of alcohol …