Cross-species models of attention-deficit/hyperactivity disorder and autism spectrum disorder: lessons from: CNTNAP2:: ADGRL3:, and: PARK2
E Dalla Vecchia, N Mortimer, VS Palladino… - … genetics, 2019 - journals.lww.com
… The zebrafish is an emerging model organism for biomedical … in most of the model organisms
used in translational research, … the similarity of this model to ADHD or ASD phenotypes. …
used in translational research, … the similarity of this model to ADHD or ASD phenotypes. …
From rare copy number variants to biological processes in ADHD
B Harich, M van der Voet, M Klein… - American Journal of …, 2020 - Am Psychiatric Assoc
… underlying ADHD. Studies in model organisms can provide a wealth of phenotypic information,
… Regulation and initiation of translation have been linked to neuropsychiatric disorders, …
… Regulation and initiation of translation have been linked to neuropsychiatric disorders, …
Habituation in high-throughput genetic model organisms as a tool to investigate the mechanisms of neurodevelopmental disorders
… , and attention deficit hyperactivity disorder (ADHD), … genetic model organisms enable
efficient and controllable protein degradation and re-expression to determine whether phenotypes …
efficient and controllable protein degradation and re-expression to determine whether phenotypes …
Modelling autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) using mice and zebrafish
… by several transcription-translation feedback loops controlling … of the preferred in vivo model
organisms for studying diverse … -related genes have been linked to ADHD phenotypes. This …
organisms for studying diverse … -related genes have been linked to ADHD phenotypes. This …
Zebrafish models for attention deficit hyperactivity disorder (ADHD)
BD Fontana, F Franscescon, DB Rosemberg… - Neuroscience & …, 2019 - Elsevier
… animal models of ADHD, their clinical and translational … the individual attention-related
phenotypes have not been examined … a critical novel model organism for ADHD research. Multiple …
phenotypes have not been examined … a critical novel model organism for ADHD research. Multiple …
Genetics of ADHD: what should the clinician know?
… genetic studies. In our review article, we provide an overview on common and rare genetic
risk variants for ADHD … PRS explain different behavioral phenotypes in ADHD and how they …
risk variants for ADHD … PRS explain different behavioral phenotypes in ADHD and how they …
Epigenetics and ADHD: reflections on current knowledge, research priorities and translational potential
… have been linked to a range of phenotypes relevant to ADHD (eg developmental delays,
cognitive and motor impairments [67, 68]), and inactivation of this gene in animals results in …
cognitive and motor impairments [67, 68]), and inactivation of this gene in animals results in …
Rodent models of attention-deficit hyperactivity disorder: An updated framework for model validation and therapeutic drug discovery
KM Kantak - Pharmacology Biochemistry and Behavior, 2022 - Elsevier
… has the most translational support at this stage to model ADHD/… rat model and the prenatal
nicotine exposure mouse model … rodent model of ADHD should include a phenotype whereby …
nicotine exposure mouse model … rodent model of ADHD should include a phenotype whereby …
Developmental genetics with model organisms
U Irion, C Nüsslein-Volhard - Proceedings of the National …, 2022 - National Acad Sciences
… The genes could be classified into groups with similar phenotypes… made use of the advantages
of this model organism (56). … These microRNAs regulate the translation of other genes by …
of this model organism (56). … These microRNAs regulate the translation of other genes by …
Review of rodent models of attention deficit hyperactivity disorder
SL Regan, MT Williams, CV Vorhees - Neuroscience & Biobehavioral …, 2022 - Elsevier
… relevant information, especially regarding the genetic basis of the disorder, this review focuses
on rodent models … interaction models that could provide new perspectives on ADHD. The …
on rodent models … interaction models that could provide new perspectives on ADHD. The …