[HTML][HTML] Crossing bacterial boundaries: The carbon catabolite repression system Crc-Hfq of Pseudomonas putida KT2440 as a tool to control translation in E. coli

C Lu, TP Ramalho, MMM Bisschops, RH Wijffels… - New …, 2023 - Elsevier
Crc-Hfq regulates benzoate degradation mainly by binding to the mRNA of BenR - the … The
translational repressor Crc controls the Pseudomonas putida benzoate and alkane catabolic

Rewiring the functional complexity between Crc, Hfq and sRNAs to regulate carbon catabolite repression in Pseudomonas

K Bharwad, S Rajkumar - World Journal of Microbiology and …, 2019 - Springer
… is under catabolic repression in Pseudomonas because organic … putida, Crc binds to
benR and alkS mRNAs and inhibit the translation leading to repression of benzoate and alkane

[HTML][HTML] … is too much of a good thing: how carbon catabolite repression and metabolic versatility impede production of esterified α, ω-diols in Pseudomonas putida …

C Lu, C Batianis, EO Akwafo, RH Wijffels… - Biotechnology for …, 2021 - Springer
… (CCR) of essential genes for uptake and catabolism of non-… Crc regulates the expression
of over 130 genes in P. … of hydrocarbons, such as n-alkanes, benzoate and toluene. …

Simultaneous carbon catabolite repression governs sugar and aromatic co-utilization in Pseudomonas putida M2

S Shrestha, D Awasthi, Y Chen, J Gin… - Applied and …, 2023 - Am Soc Microbiol
… the translation of mRNAs responsible for the catabolism of … of aromatic catabolic genes
in crc-1 and control strains when … -JD1 grown on glucose and benzoate where glucose-derived …

Degradation strategies and associated regulatory mechanisms/features for aromatic compound metabolism in bacteria

PS Phale, H Malhotra, BA Shah - Advances in Applied Microbiology, 2020 - Elsevier
… Various proteins belonging to diverse families have evolved to regulate the transcription of
individual operons participating in aromatic catabolism. These proteins, complemented with …

The acetoin assimilation pathway of Pseudomonas putida KT2440 is regulated by overlapping global regulatory elements that respond to nutritional cues

R Moreno, L Yuste, F Rojo - Environmental microbiology, 2023 - Wiley Online Library
putida KT2440 acetoin catabolism genes and to determine … Since a lack of Crc did not
fully relieve repression, the … /Crc target sites that help control the translation of these mRNAs. …

Engineering Native and Synthetic Pathways in Pseudomonas putida for the Production of Tailored Polyhydroxyalkanoates

MP Mezzina, MT Manoli, MA Prieto… - Biotechnology …, 2021 - Wiley Online Library
… are as follows: Crc, catabolite repression control protein; RpoS, … putida, carbon fluxes within
central catabolic pathways are … able to produce aliphatic PHA from benzoate, a lignin model …

Metabolic Engineering of Pseudomonas

PI Nikel, V de Lorenzo - Metabolic Engineering: Concepts and …, 2021 - Wiley Online Library
putida seems to utilize a carbon catabolite repressionputida, different pathways for xylose
catabolism have been … degradation of benzoate and m-toluate in Pseudomonas arvilla …

Direct biosynthesis of adipic acid from lignin-derived aromatics using engineered Pseudomonas putida KT2440

W Niu, H Willett, J Mueller, X He, L Kramer, B Ma… - Metabolic …, 2020 - Elsevier
… the crc gene, which encodes the carbon repression control protein in … catabolism of
aromatics by KT2440 is also subjected to translational level catabolite repression through the Crc

Lignin conversion to β-ketoadipic acid by Pseudomonas putida via metabolic engineering and bioprocess development

AZ Werner, WT Cordell, CW Lahive, BC Klein… - Science …, 2023 - science.org
… , starting with the catabolite represson control (Crc) regulator. … effect of Crc repression on
β-ketoadipate production, crc was … acid and its subsequent catabolism could be important in …