[HTML][HTML] Out of control: the role of the ubiquitin proteasome system in skeletal muscle during inflammation
… and coordinated process comprising many different pathways, … related members, including
NF-κB1 (also named p50), NF-κB2 … of the p105 and p100 precursor proteins, respectively [310,…
NF-κB1 (also named p50), NF-κB2 … of the p105 and p100 precursor proteins, respectively [310,…
[HTML][HTML] Small molecule NF-κB pathway inhibitors in clinic
V Ramadass, T Vaiyapuri, V Tergaonkar - International journal of …, 2020 - mdpi.com
… , the pathway mediated by NF-κB1/… proteins need not be ubiquitinated before degradation
like conversion of p105 to p50 in canonical NF-κB pathway or in post-translational processing. …
like conversion of p105 to p50 in canonical NF-κB pathway or in post-translational processing. …
Ubiquitination in rheumatoid arthritis
… The lysosomal pathway is involved in degradation process of … proteins which are required
for proteasomal degradation … is a 26-kDa active precursor protein) and carried out by metallo-…
for proteasomal degradation … is a 26-kDa active precursor protein) and carried out by metallo-…
[HTML][HTML] Ubiquitination in the regulation of inflammatory cell death and cancer
… system that regulate fundamental cellular processes … drugs (iMiDs) in the ubiquitin proteasome
system (UPS), and the … repeats-containing proteins), while NF-κB1 is partially degraded, …
system (UPS), and the … repeats-containing proteins), while NF-κB1 is partially degraded, …
Investigating NF-κB ubiquitination: An in vitro study
JP Mitchell - 2019 - theses.gla.ac.uk
… the components of the ubiquitin-proteasome system (UPS) … many of which have essential
roles in the immune system, which … protein, and it controls a diverse array of cellular processes (…
roles in the immune system, which … protein, and it controls a diverse array of cellular processes (…
[HTML][HTML] Interplay between proteasome inhibitors and NF-κB pathway in leukemia and lymphoma: a comprehensive review on challenges ahead of proteasome …
… The ubiquitin-proteasome system (UPS) plays a crucial role … Furthermore, the conversion
of p50 from its precursor protein … of the RelA(p65)/NF-κB1(p50) heterodimer. Another non-…
of p50 from its precursor protein … of the RelA(p65)/NF-κB1(p50) heterodimer. Another non-…
[HTML][HTML] The preliminary study suggests an association between NF-ĸB pathway activation and increased plasma 20S proteasome activity in intracranial aneurysm …
J Kamińska, M Tylicka, K Sutkowska, KM Gacuta… - Scientific Reports, 2024 - nature.com
… of NF-κB1 (p105) and NF-κB p65 precursor proteins and … on our results, indicating a
required sample size of 19 for … , which is processed to generate the mature protein. Moorthy …
required sample size of 19 for … , which is processed to generate the mature protein. Moorthy …
[HTML][HTML] The impact of NF-κB signaling on pathogenesis and current treatment strategies in multiple myeloma
D Vrábel, L Pour, S Ševčíková - Blood reviews, 2019 - Elsevier
… They are NF-κB1 (p50 and its precursor p105), NF-κB2 (p52 … of C-terminal part of precursor
protein p100; Ub – ubiquitin, P … is represented by the ubiquitin-proteasome pathway. Hence, …
protein p100; Ub – ubiquitin, P … is represented by the ubiquitin-proteasome pathway. Hence, …
Role of nuclear factor kappa B (NF-κB) signalling in neurodegenerative diseases: an mechanistic approach
S Singh, TG Singh - Current Neuropharmacology, 2020 - ingentaconnect.com
… genes encoding proteins having a vital role in processes of … is involved in the ubiquitin-proteasome
system [127, 128]. … or beta–site amyloid precursor protein cleaving enzyme 1 (BACE1…
system [127, 128]. … or beta–site amyloid precursor protein cleaving enzyme 1 (BACE1…
[HTML][HTML] NF-κB: at the borders of autoimmunity and inflammation
L Barnabei, E Laplantine, W Mbongo… - Frontiers in …, 2021 - frontiersin.org
… An essential regulatory process that controls autoreactive T-cells is mediated by the … The
ubiquitin-proteasome system plays an important role in enabling activation of NF-κB. The use of …
ubiquitin-proteasome system plays an important role in enabling activation of NF-κB. The use of …