Treatment advances in sepsis and septic shock: modulating pro-and anti-inflammatory mechanisms
… treatment options, we researched ways to optimize sepsis … regarding immune modulation
in sepsis and septic shock and … in severe disease but would be detrimental to the natural …
in sepsis and septic shock and … in severe disease but would be detrimental to the natural …
Natural killer cells in sepsis: underprivileged innate immune cells
V Kumar - European Journal of Cell Biology, 2019 - Elsevier
… immune memory and their therapeutic targeting to manage the sepsis as a future therapeutic
approach … of NK cells during sepsis, severe sepsis, and septic shock due to the decreased …
approach … of NK cells during sepsis, severe sepsis, and septic shock due to the decreased …
Emerging therapeutic targets for sepsis
EW Tindal, BE Armstead, SF Monaghan… - … on therapeutic …, 2021 - Taylor & Francis
… outcomes with this approach, Surviving Sepsis guidelines now … for patients with severe
sepsis or septic shock found that early … the innate immune system is rich in potential therapeutic …
sepsis or septic shock found that early … the innate immune system is rich in potential therapeutic …
Immunometabolism: another road to sepsis and its therapeutic targeting
V Kumar - Inflammation, 2019 - Springer
… sepsis-associated mortality is reported [4,5,6]. But still, the mortality associated with severe
sepsis and septic shock approaches … the innate immune system comprising of innate immune …
sepsis and septic shock approaches … the innate immune system comprising of innate immune …
Signaling pathways and intervention therapies in sepsis
Y Zhang, B Ning - Signal Transduction and Targeted Therapy, 2021 - nature.com
… against infection, while septic shock is defined as a subset of sepsis … In a latest global survey
of pediatric sepsis, severe sepsis … At initiation of sepsis, innate immune cells are generally …
of pediatric sepsis, severe sepsis … At initiation of sepsis, innate immune cells are generally …
[HTML][HTML] Sepsis—pathophysiology and therapeutic concepts
D Jarczak, S Kluge, A Nierhaus - Frontiers in medicine, 2021 - frontiersin.org
… update the choice of therapeutic approaches targeting different … As part of the innate immune
system, neutrophils form a … more than thousand severe sepsis and septic shock patients, it …
system, neutrophils form a … more than thousand severe sepsis and septic shock patients, it …
Inflammation and cell death of the innate and adaptive immune system during sepsis
C Nedeva - Biomolecules, 2021 - mdpi.com
… inflammatory molecules by the innate immune system, potentially … in a small percentage of
severe sepsis cases, however, our … studies of natural killer cell activity in septic shock patients. …
severe sepsis cases, however, our … studies of natural killer cell activity in septic shock patients. …
[HTML][HTML] Therapeutic approaches in modulating the inflammatory and immunological response in patients with sepsis, acute respiratory distress syndrome, and …
Y Mehta, SB Dixit, K Zirpe, R Sud, PB Gopal, PA Koul… - Cureus, 2021 - ncbi.nlm.nih.gov
… be a different therapeutic approach. Metanalyses in patients with severe sepsis or septic shock
have … response and preserve innate immunity. Over the past four decades, steroid use in …
have … response and preserve innate immunity. Over the past four decades, steroid use in …
Sepsis therapies: learning from 30 years of failure of translational research to propose new leads
… of surviving sepsis and, finally, list some putative approaches—… Reprogramming The
modified responsiveness of innate immune … Septic shock A subset of sepsis in which particularly …
modified responsiveness of innate immune … Septic shock A subset of sepsis in which particularly …
Immune deregulation in sepsis and septic shock: reversing immune paralysis by targeting PD-1/PD-L1 pathway
Y Nakamori, EJ Park, M Shimaoka - Frontiers in immunology, 2021 - frontiersin.org
… complying with the Surviving Sepsis Campaign guidelines (4… of sepsis, inflammation
originating in the innate immune … could represent a promising therapeutic approach, awaiting a …
originating in the innate immune … could represent a promising therapeutic approach, awaiting a …