Characteristics and therapeutic potential of human amnion-derived stem cells

QW Liu, QM Huang, HY Wu, GSL Zuo, HC Gu… - International journal of …, 2021 - mdpi.com
… and improve functional recovery in experimental model and clinical … hAESCs are two primary
stem cell types in amniotic membrane … hAMSCs also exerted a higher therapeutic efficacy in …

Comparison of the therapeutic effect of amniotic fluid stem cells and their exosomes on monoiodoacetate‐induced animal model of osteoarthritis

M Zavatti, F Beretti, F Casciaro, E Bertucci… - Biofactors, 2020 - Wiley Online Library
… This timing is consistent with data reported in literature26 and it was confirmed also in the
experiment shown in this paper. Then, animals were treated with vehicle (PBS), with AFSC (5 …

[HTML][HTML] Human amniotic membrane intra‑articular injection prevents cartilage damage in an osteoarthritis model

IA Marino‑Martínez… - Experimental and …, 2019 - spandidos-publications.com
… The present study evaluated the effect of intra‑articular injection of human amniotic membrane
(AM) as a treatment in an OA animal model in the knee. Chemical OA was developed in …

Comparison of miRNA cargo in human adipose-tissue vs. amniotic-membrane derived mesenchymal stromal cells extracellular vesicles for osteoarthritis treatment

E Ragni, CP Orfei, A Papait… - EXTRACELLULAR …, 2021 - publicatt.unicatt.it
… In our experimental conditions, hASCs and hAMSCs released EVs in the range of 1.6 × 103
… miRNAs from adipose- and amniotic membrane-derived MSCs, characterized with the same …

Amniotic membrane-mesenchymal stromal cells secreted factors and extracellular vesicle-miRNAs: Anti-inflammatory and regenerative features for musculoskeletal …

E Ragni, A Papait, C Perucca Orfei… - Stem Cells …, 2021 - academic.oup.com
… The therapeutic potential of human amniotic membrane-derived mesenchymal stromal cells
(hAMSCs) has been addressed to both soluble factors and extracellular vesicles (EVs). This …

Human amniotic membrane as a delivery vehicle for stem cell-based therapies

P Chen, M Lu, T Wang, D Dian, Y Zhong, M Aleahmad - Life Sciences, 2021 - Elsevier
… Stem cell-based therapy is known as a regenerative … These cells exert their therapeutic effects
through paracrine … using amniotic membrane which was loaded with human umbilical cord …

Anti-arthritogenic property of interleukin 10-expressing human amniotic MSCs generated by gene editing in collagen-induced arthritis

DS Chae, YJ Park, SW Kim - International Journal of Molecular Sciences, 2022 - mdpi.com
… the anti-arthritogenic properties of IL-10-edited human AMMs in experimental arthritis. …
Thus, the therapeutic effects of MSCs need to be enhanced for the treatment of arthritis, and we …

Reduced size profile of amniotic membrane particles decreases osteoarthritis therapeutic efficacy

DS Reece, OA Burnsed, K Parchinski… - … Engineering Part A, 2020 - liebertpub.com
… samples from five donors were pooled while in dehydrated form, and the required amount
by mass was measured from the pooled material and rehydrated for each experiment in this …

Human amniotic suspension allograft improves pain and function in knee osteoarthritis: a prospective not randomized clinical pilot study

S Natali, L Farinelli, D Screpis, D Trojan… - Journal of Clinical …, 2022 - mdpi.com
… responsible committee on human experimentation (institutional … Subsequently, the amniotic
membrane is transferred in … for the treatment of pain and improves knee function in OA. As …

[HTML][HTML] Application of amniotic membrane in osteoarthritis management

Z Macečková, J Pergner, M Krbec, M Urban… - Journal of Cartilage & …, 2024 - Elsevier
… of the pharmacological mechanisms underlying the therapeutic effects of these AM-derived
products. It was shown that amniotic membrane homogenate inhibited MMP-2 and MMP-9 …