… TLRs in infectious diseases, cancers, and autoimmune diseases and therapeutic regimens
… Toll-like receptors are employed as therapeutic targets as well as vaccine adjuvants in viral …

… and signaling mechanisms of Toll-like receptors. A, A typical … Therapeutics targeting
immune-related diseases mediated … cancers, viral infection, immune diseases, and inflammation. …

… the risk for inflammatory diseases and autoimmune disorders. Antagonists/inhibitors targeting
the TLR signaling pathways have emerged as novel therapeutics to treat these diseases. …

… Toll-like receptors (TLRs) … infections as well as cancers. Nonetheless, deregulated signaling
can have detrimental effects on the host, in the form of inflammatory or autoimmune diseases…

… of this receptor and how it participates in various aspects of cancer progression. … cancer
studies to suggest the therapeutic potential of this receptor for future targeted therapies…

… Due to their ability to link the innate with the adaptive immune response, Toll-like receptor
(… complex diseases such as cancer, AIDS and malaria. TLRs are transmembrane receptors, …

… TLRs as Therapeutic Targets in Cancers The therapeutic targeting of TLRs in cancer has …
activities of several TLRs in certain cancer types and the resultant clinical setbacks [228]. The …

… infections to cancer, from metabolic disorders to neurodegeneration and autoimmune
diseases… lead compound for the identification of novel therapeutics targeting TLR5. (108) In …

… against infection and tissue damage. This superfamily of receptors including Toll-like receptors
(… This potentially offers a number of therapeutic targets in chronic inflammatory diseases. …

… At present, a number of CAR-T-cell therapy targets have been reported in glioma treatment,
… ], and therefore can be used as potential targets in cancer therapy. This review reports TLR …