Comparative study of different crystallization methods in the case of cilostazol crystal habit optimization

T Tari, P Szabó-Révész, Z Aigner - Crystals, 2019 - mdpi.com
cilostazol is limited owing to its poor aqueous solubility and oral bioavailability. Our aim was
to produce cilostazol … size distribution and stable polymorphic form to increase its dissolution …

Crystal habit optimization by means of impinging jet crystallization method

T Tari - 2019 - search.proquest.com
polymorph, Forms B and C are metastable, and Form C has a monoclinic crystal structure
[93]. Cilostazol … bioavailability, the therapeutic usage of cilostazol is limited. Therefore, several …

Hydrophilic sugars for enhancing dissolution rate of cilostazol: effect of wet co-processing

AY Bazeed, A Nouh, EA Essa… - …, 2020 - article.journalrepositoryarticle.com
… cooling of cilostazol is believed to result in polymorphic transition… It may possibly reflect
polymorphic transition of the drug in … Polymorphism has been reported for cilostazol upon thermal …

Molecular dynamics simulation, thermodynamic parameters and solute–solvent molecular interactions of cilostazol (form A) dissolution in (ethylene glycol/ethanol+ …

G Xia, Z Luo, Y Yang, L Chen, R Li, C Du… - The Journal of Chemical …, 2024 - Elsevier
… adopted to analyze the crystalline form of the raw materials and equilibrium solid phase
after experiments in each systems. The equilibrated cilostazol was recovered from equilibrium …

A systematic approach to the development of cilostazol nanosuspension by liquid antisolvent precipitation (LASP) and its combination with ultrasound

E Jakubowska, B Milanowski, J Lulek - International Journal of Molecular …, 2021 - mdpi.com
… has been able to generate any polymorphic form other than A for cilostazol, unlike for many
… govern the resulting crystalline form [81]. The chemical identity of cilostazol in every sample …

[PDF][PDF] Department of pharmaceutics, faculty of pharmacy, university of Kufa, Al-Najaf, Iraq. 2 Department of pharmaceutics, Collage of pharmacy, Mustansiriyah …

AN Wannas, NK Maraie, MHM Ali… - Journal of Natural …, 2021 - alrasheedcol.edu.iq
… maintained>90% of cilostazol in the solubilized form after 3 hours in non- … to prepare cilostazol
liquid oral dosage form using … Thermallyprepared polymorphic forms of cilostazol. J Pharm …

Electrospun poly (lactic acid)(PLA)/poly (butylene adipate-co-terephthalate)(PBAT) nanofibers for the controlled release of cilostazol

LR Antunes, GL Breitenbach, MCG Pellá… - International Journal of …, 2021 - Elsevier
… Pure cilostazol presented peaks at 2θ angles of about 9.2, 12.8, 15.5, 18.6, 19.3, and 31.4
[… of form A of cilostazol [45]. However, the mixture of the three polymorphic forms [41,46] in the …

クリスタルエンジニアリングに基づく超微粉体の開発

長井紀章 - ホソカワ粉体工学振興財団年報, 2020 - jstage.jst.go.jp
… In this study, we prepared the nanocrystal based on crystal polymorph of cilostazol (CLZ),
and found that the crystal polymorph affected the solubility, stability and bioavailability in the …

Einfluss von Cilostazol auf die Frakturheilung im murinen Ischämiemodell

J Stutz - 2020 - publikationen.sulb.uni-saarland.de
… 2 weeks after cilostazol treatment, the bending stiffness was significantly lower compared to
… significantly higher after cilostazol treatment. In conclusion, cilostazol delays fracture healing …