[HTML][HTML] MatchTope: A tool to predict the cross reactivity of peptides complexed with Major Histocompatibility Complex I
…, P Vianna, MV de Freitas, I Pöhner… - Frontiers in …, 2022 - frontiersin.org
… sequences binding to the Major Histocompatibility Complex (pMHC). However, few of
these bioinformatics tools take into account the pMHC three-dimensional structure. Here, we …
these bioinformatics tools take into account the pMHC three-dimensional structure. Here, we …
Hydrophobic core evolution of major histocompatibility complex class I chain-related protein a for dramatic enhancing binding affinity
W Cai, S Peng, Y Tian, Y Bao, Q Liu, Y Dong… - International Journal of …, 2024 - Elsevier
… cell stress molecule, major histocompatibility complex class I … killer group 2D (NKG2D)
homodimer to form three molecule … Crystal structures of the NKG2D–MICA variant complexes …
homodimer to form three molecule … Crystal structures of the NKG2D–MICA variant complexes …
[HTML][HTML] The ABC of major histocompatibility complexes and T cell receptors in health and disease
K Kedzierska, M Koutsakos - Viral Immunology, 2020 - liebertpub.com
… While antibodies bind to three-dimensional epitopes on … glycoprotein called major
histocompatibility complexes (MHCs) (… -encoded antigen-presenting molecules and foreign …
histocompatibility complexes (MHCs) (… -encoded antigen-presenting molecules and foreign …
Major Histocompatibility Complex and Antigen Presentation
S Beri, N Garg - An Interplay of Cellular and Molecular …, 2022 - taylorfrancis.com
… FIGURE 7.7 (A) The three dimensional protein structure of Class I MHC molecule. (b) The
antigen binding site of Class I MHC molecule with the antigen is highlighted in yellow. …
antigen binding site of Class I MHC molecule with the antigen is highlighted in yellow. …
Four Faces of cell-surface HLA Class-I: Their antigenic and immunogenic divergence generating novel targets for Vaccines
MH Ravindranath, NM Ravindranath, SR Selvan… - Vaccines, 2022 - mdpi.com
… with the three-dimensional structure of a peptide carried on an HLA class-I or -II molecule. …
The HLA-II β chain of Face-1 contains only an N-linked, complex-type carbohydrates chain. …
The HLA-II β chain of Face-1 contains only an N-linked, complex-type carbohydrates chain. …
Ancient features of the MHC class II presentation pathway, and a model for the possible origin of MHC molecules
JM Dijkstra, T Yamaguchi - Immunogenetics, 2019 - Springer
… Major histocompatibility complex (MHC) molecules are only found in jawed vertebrates and
not in … MHC class II type structures likely represent the ancestral structure of MHC molecules. …
not in … MHC class II type structures likely represent the ancestral structure of MHC molecules. …
Combining three-dimensional modeling with artificial intelligence to increase specificity and precision in peptide–MHC binding predictions
… into the four binding classes based on their experimental binding affinities (ie… class, we
aligned the structures of all the p–MHC complexes in each class to the reference crystal structure …
aligned the structures of all the p–MHC complexes in each class to the reference crystal structure …
Molecular histocompatibility beyond tears: The next generation version
… HLA typing by molecular sequencing techniques revolutionized our understanding of the …
molecules at the population level. Together with deciphering the three-dimensional structure, it …
molecules at the population level. Together with deciphering the three-dimensional structure, it …
Selective Inhibitors of T Cell Receptor Recognition of Antigen–MHC Complexes for Rheumatoid Arthritis
… major histocompatibility complex (MHC) of class II in complex … previously reported three-dimensional
model structure of the … recognition of antigen-HLA complex in RA were identified by …
model structure of the … recognition of antigen-HLA complex in RA were identified by …
Deep neural networks predict class I major histocompatibility complex epitope presentation and transfer learn neoepitope immunogenicity
… three-dimensional structure of an MHC molecule of interest. The mean attention for each
pseudosequence position per allele in the EL evaluation dataset is illustrated in Extended Data …
pseudosequence position per allele in the EL evaluation dataset is illustrated in Extended Data …