Fibrinolysis in patients with liver disease

FA von Meijenfeldt, T Lisman - Seminars in thrombosis and …, 2021 - thieme-connect.com
thrombin activatable fibrinolysis inhibitor; tPA, tissue-type plasminogen activator; PAI-1,
plasminogen activator inhibitor-… This is, in part, because we lack well-validated tests of fibrinolysis

[PDF][PDF] Fibrinolysis shutdown is associated with thrombotic and hemorrhagic complications and poorer outcomes after liver transplantation

R Nicolau‐Raducu, T Beduschi, R Vianna… - Liver …, 2019 - Wiley Online Library
Thrombin-activatable fibrinolysis inhibitor deficiency in cirrhosis is not associated with
increased plasma fibrinolysis. Gastroenterology 2001;121:131-139. 7) Leonardi F, Maria N, Villa E…

[PDF][PDF] More pronounced hypercoagulable state and hypofibrinolysis in patients with cirrhosis with versus without HCC

A Zanetto, E Campello, C Bulato… - Hepatology …, 2021 - Wiley Online Library
inhibitor- 1 antigen (PAI- 1; nv 1- 25 ng/mL), tissue plasminogen activator antigen (t- PA, nv
<10 ng/mL), and activated inactivated thrombin- activatable fibrinolysis inhibitor … for the lack of …

Fibrin clot quality in acutely ill cirrhosis patients: relation with outcome and improvement with coagulation factor concentrates

A Blasi, VC Patel, ENHE Spanke… - Liver …, 2022 - Wiley Online Library
… as acute kidney injury which has been linked to a specific exaggeration of FXIII deficiency in
… to fibrinolysis due to enhanced activation of thrombin-activatable fibrinolysis inhibitor (TAFI). …

Altered clot formation and lysis are associated with increased fibrinolytic activity in ascites in patients with advanced cirrhosis

S Gitto, RG Romanelli, AP Cellai, D Lami… - Internal and emergency …, 2021 - Springer
… contribution of thrombin-activatable fibrinolysis inhibitor (TAFI… carboxypeptidase inhibitor
(CPI) (25 μl/ml), a specific inhibitor … The role of TAFI deficiency on plasma fibrinolysis in cirrhotic

[HTML][HTML] Fibrin clot properties and thrombus composition in cirrhosis

EG Driever, T Lisman - Research and practice in thrombosis and …, 2023 - Elsevier
… These tests, however, are only sensitive to deficiencies or defects in … with cirrhosis has
been linked to decreased levels of antiplasmin and thrombin-activatable fibrinolysis inhibitor or …

[PDF][PDF] VWF/ADAMTS13 imbalance, but not global coagulation or fibrinolysis, is associated with outcome and bleeding in acute liver failure

EG Driever, RT Stravitz, J Zhang, J Adelmeijer… - …, 2021 - Wiley Online Library
… have demonstrated that patients with liver disease are in a … who have an isolated ADAMTS13
deficiency. Specifically, despite a … inhibitor 1 and decreased levels of thrombin activatable

Fresh frozen plasma transfusion in patients with cirrhosis and coagulopathy: effect on conventional coagulation tests and thrombomodulin-modified thrombin …

AB Rassi, EA d'Amico, A Tripodi, TRF da Rocha… - Journal of …, 2020 - Elsevier
… The efficacy of fresh frozen plasma (FFP) transfusion in enhancing thrombin generation in
patients with cirrhosis and impaired conventional coagulation tests has not been sufficiently …

Severe antithrombin deficiency may be associated with a high risk of pathological progression of DIC with suppressed fibrinolysis

H Wada, G Honda, N Kawano… - Clinical and Applied …, 2020 - journals.sagepub.com
Thrombin-activatable fibrinolytic inhibitor and PAI-1 were not measured in the present study
because data from PMS in daily clinical practice did not include the special coagulation tests …

Impact of alcohol use disorder treatment on clinical outcomes among patients with cirrhosis

S Rogal, A Youk, H Zhang, WF Gellad, MJ Fine… - Hepatology, 2020 - journals.lww.com
… As for fibrinolysis, increased tissue‐type and urokinase‐type plasminogen activators, a …
activator inhibitor 1, and decreased levels of thrombinactivatable fibrinolysis inhibitor and α2‐…