[HTML][HTML] Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis
IM Tleyjeh, Z Kashour, M Damlaj, M Riaz… - Clinical Microbiology …, 2021 - Elsevier
… 1325 patients, examined the effect of tocilizumab on short-term … 771 patients examined
the effect of tocilizumab on risk of … as rheumatoid arthritis, systemic lupus erythematosus (SLE), …
the effect of tocilizumab on risk of … as rheumatoid arthritis, systemic lupus erythematosus (SLE), …
Biological therapies and their clinical impact in the treatment of systemic lupus erythematosus
R Magro - Therapeutic Advances in Musculoskeletal …, 2019 - journals.sagepub.com
… A phase I open-label study assessed the clinical and immunological efficacy of tocilizumab
… Despite the promising preliminary results in terms of efficacy no further phase II randomized …
… Despite the promising preliminary results in terms of efficacy no further phase II randomized …
Tocilizumab for massive refractory pleural effusion in an adolescent with systemic lupus erythematosus
A De Matteis, E Sacco, C Celani, A Uva, V Messia… - Pediatric …, 2021 - Springer
… tocilizumab (800 mg every two weeks) was started with prompt recovery of pleural effusion.
… of our knowledge, this is the first case of JSLE pleuritis successfully treated with tocilizumab. …
… of our knowledge, this is the first case of JSLE pleuritis successfully treated with tocilizumab. …
Tocilizumab Therapy for Treatment-Resistant Systemic Lupus Erythematosus with Elevated IL-6 and CRP Levels: A Case Report
… TCZ exerts its immunomodulatory effects and has been shown … tocilizumab. However, the
subsequent randomized control phase 2 trial of IL 6 blockade did not show anticipated efficacy …
subsequent randomized control phase 2 trial of IL 6 blockade did not show anticipated efficacy …
Can tocilizumab calm the cytokine storm of COVID-19?
GS Schulert - The Lancet Rheumatology, 2020 - thelancet.com
… for treatment of severe COVID-19 patients: preliminary … underpowered for key safety and
efficacy outcomes.This study … with juvenile-onset systemic lupus erythematosus (SLE), the …
efficacy outcomes.This study … with juvenile-onset systemic lupus erythematosus (SLE), the …
Safety and efficacy of intravenous belimumab in children with systemic lupus erythematosus: results from a randomised, placebo-controlled trial
HI Brunner, C Abud-Mendoza, DO Viola… - Annals of the …, 2020 - ard.bmj.com
… . The effect of combined estrogen and progesterone hormone replacement therapy on
disease activity in systemic lupus erythematosus: a randomized trial. Ann Intern Med 2005;142:…
disease activity in systemic lupus erythematosus: a randomized trial. Ann Intern Med 2005;142:…
Systemic lupus erythematosus: an expert insight into emerging therapy agents in preclinical and early clinical development
M Tocut, Y Shoenfeld… - Expert Opinion on …, 2020 - Taylor & Francis
… Dose-dependent adverse effects without increasing drug efficacy included a higher risk
for viral infections such as herpes zoster reactivation and influenza, most noted in the highest …
for viral infections such as herpes zoster reactivation and influenza, most noted in the highest …
A systematic literature review informing the consensus statement on efficacy and safety of pharmacological treatment with interleukin-6 pathway inhibition with …
K Kastrati, D Aletaha, GR Burmester, E Chwala… - RMD open, 2022 - rmdopen.bmj.com
… Use of tocilizumab resulted in better clinical outcomes and … Preliminary results from ongoing
clinical trials, which were … for the treatment of systemic lupus erythematosus: a phase II dose-…
clinical trials, which were … for the treatment of systemic lupus erythematosus: a phase II dose-…
Biological therapy in systemic lupus erythematosus, antiphospholipid syndrome, and Sjögren's syndrome: evidence-and practice-based guidance
A Marinho, J Delgado Alves, J Fortuna, R Faria… - Frontiers in …, 2023 - frontiersin.org
… Preliminary recommendations were drafted by working groups for each disease. A … outcomes
in patients with arthritis flares (88, 89) or with refractory serositis (90, 91). Tocilizumab was …
in patients with arthritis flares (88, 89) or with refractory serositis (90, 91). Tocilizumab was …
Monoclonal antibodies targeting interleukins for systemic lupus erythematosus: updates in early clinical drug development
C Cruciani, M Gatto, L Iaccarino, A Doria… - Expert Opinion on …, 2024 - Taylor & Francis
… may be discovered which could affect the content, and all legal … A phase II trial testing the
efficacy and safety of a new anti-… regarding the safety of intravenous Tocilizumab administered …
efficacy and safety of a new anti-… regarding the safety of intravenous Tocilizumab administered …