… 1325 patients, examined the effect of tocilizumab on short-term … 771 patients examined
the effect of tocilizumab on risk of … as rheumatoid arthritis, systemic lupus erythematosus (SLE), …

… A phase I open-label study assessed the clinical and immunological efficacy of tocilizumab
… Despite the promising preliminary results in terms of efficacy no further phase II randomized …

… tocilizumab (800 mg every two weeks) was started with prompt recovery of pleural effusion.
… of our knowledge, this is the first case of JSLE pleuritis successfully treated with tocilizumab. …

… TCZ exerts its immunomodulatory effects and has been shown … tocilizumab. However, the
subsequent randomized control phase 2 trial of IL 6 blockade did not show anticipated efficacy …

… for treatment of severe COVID-19 patients: preliminary … underpowered for key safety and
efficacy outcomes.This study … with juvenile-onset systemic lupus erythematosus (SLE), the …

… . The effect of combined estrogen and progesterone hormone replacement therapy on
disease activity in systemic lupus erythematosus: a randomized trial. Ann Intern Med 2005;142:…

… Dose-dependent adverse effects without increasing drug efficacy included a higher risk
for viral infections such as herpes zoster reactivation and influenza, most noted in the highest …

… Use of tocilizumab resulted in better clinical outcomes and … Preliminary results from ongoing
clinical trials, which were … for the treatment of systemic lupus erythematosus: a phase II dose-…

… Preliminary recommendations were drafted by working groups for each disease. A … outcomes
in patients with arthritis flares (88, 89) or with refractory serositis (90, 91). Tocilizumab was …

… may be discovered which could affect the content, and all legal … A phase II trial testing the
efficacy and safety of a new anti-… regarding the safety of intravenous Tocilizumab administered …