… They circumvent conventional antigen recognition by cross-linking major histocompatibility
complex class II (MHC II) molecules on antigen presenting cells (APCs) with T cell receptors (…

… cross-linking major histocompatibility complex class II (MHC II) molecules on antigen … Toxic
shock syndrome toxin-1 complexed with a class II major histocompatibility molecule HLA-DR1…

… bind simultaneously to the HLA class II molecule on antigen-… between murine major
histocompatibility class II (MHC II) and … Previous models of TSS in HLA-DR1 mice required d-…

… of the major histocompatibility complex (MHC) class II triggers … multi-organ failure in toxic
shock syndrome to autoimmune … corresponding to the expected molecular weight of the MS473 …

… molecules, the variable portion of the β chain of the T cell receptor (TCR) and the major
histocompatibility complex type II molecules (MHC-II… the highly lethal Toxic Shock Syndrome (TSS…

… human leukocyte antigen class I (HLA-I) complex as a receptor for two members (Epx2 and
Epx3), which preferentially recognize human HLA-I and homologous MHC-I of equine, bovine…

… food poisoning, and toxic shock syndrome toxin-1 (TSST-1), … toxins possess a low-affinity
α-chain major histocompatibility … -peptide complex was examined using soluble HLA-DR1 …

… on major histocompatibility complex class II (MHC class II) on … However, by crosslinking MHC
class II molecules, APCs can … aureus (S.aureus) toxic shock syndrome toxin (TSST) and S. …

… , and up to two major histocompatibility complex (MHC) binding sites (106). … Toxic shock
syndrome toxin-1 … and to emphasize its association to toxic shock syndrome (TSS). TSS is an …

… linking major histocompatibility complex class II molecules on … exotoxin C (SpeC) and toxic
shock syndrome toxin-1 (TSST-1). … selective, including toxic shock syndrome toxin-1 (TSST-1), …