Structure-toxicity relationships, toxicity mechanisms and health risk assessment of food-borne modified deoxynivalenol and zearalenone: A comprehensive review

Q Lu, JY Luo, HN Ruan, CJ Wang, MH Yang - Science of the Total …, 2022 - Elsevier
toxicity of these two toxins as well as their modified forms have … So far, the toxicity of modified
mycotoxins, especially their … to evaluate the toxicity of DON and its acetylation products—…

Determination of zearalenone and trichothecenes, including deoxynivalenol and its acetylated derivatives, nivalenol, T-2 and HT-2 toxins, in wheat and wheat …

AD Girolamo, B Ciasca, M Pascale, VMT Lattanzio - Toxins, 2020 - mdpi.com
… Similarly, toxicity studies have shown that NIV has anorectic effects upon short-term … to the
presence of DON, its acetylated derivatives (3- and 15-AcDON) and the modified form DON-3-…

Effects of deoxynivalenol, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol on parameters associated with oxidative stress in HepG2 cells

A Juan-García, C Juan, J Tolosa, MJ Ruiz - Mycotoxin Research, 2019 - Springer
… effect of deoxynivalenol (DON) and two of its acetylated analogs (… it is appropriate for EFSA
to assess the acute toxicity of DON in addition to the chronic toxicity and to assess the toxicity

Deoxynivalenol and its modified forms: Key enzymes, inter-individual and interspecies differences in metabolism

Y Wang, J Li, X Wang, W Wu… - Drug Metabolism …, 2022 - Taylor & Francis
its modified forms between individuals and species. This work provides important insight into
the toxicity of DON and its … the major metabolite of DON and its acetylated forms. However, …

Updated Review of the Toxicity of Selected Fusarium Toxins and Their Modified Forms

A Pierzgalski, M Bryła, J Kanabus, M Modrzewska… - Toxins, 2021 - mdpi.com
… Fusarium toxins and their modified forms. Deoxynivalenol (DON) and its metabolites can …
higher cytotoxicity of DON compared with that of its acetylated forms. The study by A. Juan-…

Progress in research on contamination, toxicity and transformation of acetylated deoxynivalenol.

R Wang, M Li, E Guan, Y Liu, R Jin, K Bian, S Zhao - 2023 - cabidigitallibrary.org
… Risks to human and animal health related to the presence of deoxynivalenol and its
acetylated and modified forms in food and feed[J]. EFSA Journal, 2017, 15(9): e04718. DOI:10.2903/j…

Deoxynivalenol: insights on genetics, analytical methods and occurrence

LTP Pereira, P Putnik, CHT Iwase… - Current opinion in food …, 2019 - Elsevier
… important for modification in chemical structure and toxicity. … Deoxynivalenol (DON) and its
acetylated derivatives are type … relevant modified form of DON is the conjugate deoxynivalenol-…

Deoxynivalenol: Toxicological profiles and perspective views for future research

H Zhou, T Guog, H Dai, Y Yu… - World Mycotoxin …, 2020 - wageningenacademic.com
… Risks to human and animal health related to the presence of deoxynivalenol and its acetylated
and modified forms in food and feed. EFSA Journal 15: e04718. Ficheux, AS, Sibiril, Y. …

The role of roughage provision on the absorption and disposition of the mycotoxin deoxynivalenol and its acetylated derivatives in calves: From field observations to …

B Valgaeren, L Théron, S Croubels, M Devreese… - … of toxicology, 2019 - Springer
… the absorption and biodegradation of DON and its acetylated forms in calves are lacking,
formed … and absolute oral bioavailability of DON and its acetylated derivatives (3-ADON and 15-…

Deoxynivalenol: Masked forms, fate during food processing, and potential biological remedies

H Guo, J Ji, J Wang, X Sun - … reviews in food science and food …, 2020 - Wiley Online Library
… We also show the toxicity of masked forms of DON and future … Modified forms of DON, as
well as their metabolism and … Among them, the acetylated and glycosylation forms are the most …