… transactivation domain (C-TAD) domain on N803 in HIF-1α … transcription target genes of the
hypoxia-inducible factor [11], … the extracellular environment by modulating the expression of …

… The modulation of HIF‑1α can reduce sorafenib … the transcription factor hypoxia-inducible
factor (HIF) enables cancer cells to adapt to the hypoxic environment via the transactivation of …

… elements (HRE) loci or of new active DNA regions at hypoxia inducible factors [16]. … HIF1A
inhibition in normoxia and hypoxia conditions. We found that HIF1A transcription response in …

… Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that … to pathogens through the
modulation of immune cell functions… HIF-1α contains two transactivation domains: the N-terminal …

… these domains, HIF-1α also contains two transactivation domains … of HIF-1α, while C-TAD
facilitates the transcription of … protein interactions or modulate the factors influencing these PPIs …

… HIFs are oxygen-regulated transcription factors that directly or … the HIF-α transactivation
domain (Asn-803 in human HIF-1α), … FM19G11, a new hypoxia-inducible factor (HIF) modulator, …

… a family of transcription factors, Hypoxia-inducible factors (HIFs… The hypoxia-inducible
transactivation capability of HIF-1 is … efforts have been made to modulate and intervene each step …

… modulated by transcription factors such as Nuclear Factor-… C-terminal transactivation domain
(Asn803 on HIF-1α), thereby … inhibition of HIF-hydroxylases induces transcription of genes …

… of the alpha subunits of the hypoxia inducible factors (HIFα) and the … -1α and affecting the
activity of HIF-1, by modulating its transactivation ability and not the expression levels of HIF-1α…

… that this factor could regulate the transcription of various … Transactivation and inhibitory
domains of hypoxia-inducible … Modulation of transcriptional activity by oxygen tension. J Biol …