Transcriptional regulation in non-alcoholic fatty liver disease
S Steensels, J Qiao, BA Ersoy - Metabolites, 2020 - mdpi.com
… Regardless of the source of the hit (s), hepatic responses to extrahepatic stimuli are controlled
by well-described transcriptionally regulated pathways that help transcribe the relevant …
by well-described transcriptionally regulated pathways that help transcribe the relevant …
Epigenetic regulation of hepatic lipogenesis: Role in hepatosteatosis and diabetes
J Viscarra, HS Sul - Diabetes, 2020 - Am Diabetes Assoc
… LXRs are responsive to both insulin and metabolites and function in the transcriptional
regulation of lipogenesis. LXR forms heterodimers with retinoid X receptor (RXR) and binds to …
regulation of lipogenesis. LXR forms heterodimers with retinoid X receptor (RXR) and binds to …
Integrative analysis reveals multiple modes of LXR transcriptional regulation in liver
L Bideyan, W Fan… - Proceedings of the …, 2022 - National Acad Sciences
… accessibility, gene expression, and transcription factor binding. We reveal distinct mechanisms
of LXR transcriptional regulation of both metabolic and nonmetabolic genes in liver. We …
of LXR transcriptional regulation of both metabolic and nonmetabolic genes in liver. We …
[HTML][HTML] Unraveling the regulation of hepatic gluconeogenesis
X Zhang, S Yang, J Chen, Z Su - Frontiers in endocrinology, 2019 - frontiersin.org
… We review here the molecular mechanisms underlying the transcriptional regulation of
gluconeogenesis in response to nutritional and hormonal changes. The nutrient state determines …
gluconeogenesis in response to nutritional and hormonal changes. The nutrient state determines …
Regulation of hepatic metabolism and cell growth by the ATF/CREB family of transcription factors
A Cui, D Ding, Y Li - Diabetes, 2021 - Am Diabetes Assoc
… transcriptional regulator and plays roles in hepatic glucose metabolism (29). The proteolytic
cleavage and acetylation modification of CREBH are regulated by … to control hepatic glucose …
cleavage and acetylation modification of CREBH are regulated by … to control hepatic glucose …
The regulation of hepatic fatty acid synthesis and partitioning: the effect of nutritional state
L Hodson, PJ Gunn - Nature Reviews Endocrinology, 2019 - nature.com
… Regulation of DNL occurs via transcriptional regulation of ACC and FAS, primarily by sterol
regulatory element-binding protein 1c (SREBP1c) and carbohydrate-responsive element-…
regulatory element-binding protein 1c (SREBP1c) and carbohydrate-responsive element-…
[HTML][HTML] Nuclear receptors and transcriptional regulation in non-alcoholic fatty liver disease
… transcriptional regulation. The fourth group is composed of orphan receptors whose
endogenous ligands remain uncertain, including estrogen-related receptor (ERR), constitutive …
endogenous ligands remain uncertain, including estrogen-related receptor (ERR), constitutive …
[HTML][HTML] Regulation of hepatic autophagy by stress-sensing transcription factor CREBH
H Kim, D Williams, Y Qiu, Z Song, Z Yang… - The FASEB …, 2019 - ncbi.nlm.nih.gov
… In summary, we identified CREBH as a key transcriptional regulator of hepatic autophagy
and lysosomal biogenesis for the purpose of maintaining hepatic lipid homeostasis under …
and lysosomal biogenesis for the purpose of maintaining hepatic lipid homeostasis under …
Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene
… This report demonstrates that Insig may act as a novel substrate for AMPK in regulating
hepatic lipogenesis and maintaining lipid metabolism through a post-translational modification. …
hepatic lipogenesis and maintaining lipid metabolism through a post-translational modification. …
A cellular perspective of adipogenesis transcriptional regulation
W Kuri‐Harcuch, C Velez‐delValle… - Journal of cellular …, 2019 - Wiley Online Library
… data described on transcription factors that regulate adipose differentiation, outside of those
that were reported earlier as part of the canonical adipogenic transcriptional cascade, which …
that were reported earlier as part of the canonical adipogenic transcriptional cascade, which …
相关搜索
- epigenetic regulation hepatic lipogenesis
- transcription factor hepatic lipogenesis
- non-alcoholic fatty liver disease transcriptional regulation
- target gene hepatic lipogenesis
- regulation of hepatic fatty acid synthesis
- transcriptional regulation of metabolic pathways
- transcriptional regulatory cascade
- regulation of hepatic glucose metabolism
- transcriptional regulation of adipogenesis
- regulation of hepatic gluconeogenesis
- srebp 1c phosphorylation hepatic lipogenesis
- gene regulation human macrophages
- adipocyte differentiation transcriptional control
- transcriptional regulator lipid metabolism
- regulation of phosphoenolpyruvate carboxykinase gene expression
- hepatic gene expression profiles