[HTML][HTML] Multi-walled carbon nanotubes inhibit estrogen receptor expression in vivo and in vitro through transforming growth factor beta1
LC Smith, S Moreno, S Robinson, M Orandle… - NanoImpact, 2019 - Elsevier
… whether estrogen signaling in the lung is a target … -β1 in MWCNT-induced repression of
estrogen receptor mRNA expression, we characterized the response in bronchial epithelial cells (…
estrogen receptor mRNA expression, we characterized the response in bronchial epithelial cells (…
MicroRNA let-7 downregulates ligand-independent estrogen receptor–mediated male-predominant pulmonary fibrosis
S Elliot, S Periera-Simon, X Xia, P Catanuto… - American journal of …, 2019 - atsjournals.org
… -induced lung fibrosis, suggesting a role for growth factors in … target ER (estrogen
receptor) expression in breast cancer … -like growth factor 1) (R&D Systems), TGF-β1 (transforming …
receptor) expression in breast cancer … -like growth factor 1) (R&D Systems), TGF-β1 (transforming …
[HTML][HTML] Transforming growth factor-β in tumour development
CB Trelford, L Dagnino… - Frontiers in Molecular …, 2022 - frontiersin.org
… survival by activating mechanistic target of rapamycin (mTOR). … Transforming growth factor-β
(TGFβ) signalling is tightly … adherens junctions observed in epithelial cells, whereas TWIST …
(TGFβ) signalling is tightly … adherens junctions observed in epithelial cells, whereas TWIST …
Targeting transforming growth factor-β receptors in pulmonary hypertension
C Guignabert, M Humbert - European Respiratory Journal, 2021 - Eur Respiratory Soc
… that target three well-identified pathways of endothelial cell … ) and transforming growth
factor-β (TGF-β) signalling pathways … Elevated levels of plasma transforming growth factor-β1 in …
factor-β (TGF-β) signalling pathways … Elevated levels of plasma transforming growth factor-β1 in …
Estrogen receptor beta 1: a potential therapeutic target for female triple negative breast cancer
P Dey, A Wang, Y Ziegler, S Kumar, S Yan… - …, 2022 - academic.oup.com
… The SNAIL and SLUG (SNAI2) genes encode Snail family transcription factors that downregulate
E-… significance involving hormone responsiveness and KRAS signaling represented in …
E-… significance involving hormone responsiveness and KRAS signaling represented in …
Structure, unique biological properties, and mechanisms of action of transforming growth factor β
… Transforming growth factor β (TGF-β) is a ubiquitous molecule. It is a 25-kDa homodimeric
protein composed of two identical disulfide-linked 12.5-kDa polypeptide chains that are …
protein composed of two identical disulfide-linked 12.5-kDa polypeptide chains that are …
TGF-β1–a truly transforming growth factor in fibrosis and immunity
M Lodyga, B Hinz - Seminars in cell & developmental biology, 2020 - Elsevier
… signalling (ie, depending on the signalling state of the target cell) is one reason why TGF-β1 …
, promotes vessel maturation and inhibits the growth and migration of epithelial cells [68]. As …
, promotes vessel maturation and inhibits the growth and migration of epithelial cells [68]. As …
[HTML][HTML] Estrogen receptors in epithelial-mesenchymal transition of prostate cancer
E Di Zazzo, G Galasso, P Giovannelli, M Di Donato… - Cancers, 2019 - mdpi.com
… in epithelial cells from BPH specimens. Such a process, however, was correlated to abnormalities
in ER and transforming growth factor (TGF)-β signaling, … of new targets for therapeutic …
in ER and transforming growth factor (TGF)-β signaling, … of new targets for therapeutic …
[HTML][HTML] Reprogramming of mesothelial-mesenchymal transition in chronic peritoneal diseases by estrogen receptor modulation and TGF-β1 inhibition
RB Wilson, R Archid, MA Reymond - International Journal of Molecular …, 2020 - mdpi.com
… -α receptors and block transforming growth factor-1 (TGF-β1)… the YAP target genes connective
tissue growth factor (CTGF) … the epithelial cells of PDAC, which was mediated via the cell …
tissue growth factor (CTGF) … the epithelial cells of PDAC, which was mediated via the cell …
Aggravation of pulmonary fibrosis after knocking down the aryl hydrocarbon receptor in the insulin‐like growth factor 1 receptor pathway
SM Wu, JJ Tsai, HC Pan, JL Arbiser… - British Journal of …, 2022 - Wiley Online Library
… The AhR/IGF1R axis is a potential target for the treatment of lung injury and … transforming
growth factor beta … This study on Beas2B cells showed that BLM and TGF-β1 markedly induced …
growth factor beta … This study on Beas2B cells showed that BLM and TGF-β1 markedly induced …