[HTML][HTML] Multi-walled carbon nanotubes inhibit estrogen receptor expression in vivo and in vitro through transforming growth factor beta1

LC Smith, S Moreno, S Robinson, M Orandle… - NanoImpact, 2019 - Elsevier
… whether estrogen signaling in the lung is a target … -β1 in MWCNT-induced repression of
estrogen receptor mRNA expression, we characterized the response in bronchial epithelial cells (…

MicroRNA let-7 downregulates ligand-independent estrogen receptor–mediated male-predominant pulmonary fibrosis

S Elliot, S Periera-Simon, X Xia, P Catanuto… - American journal of …, 2019 - atsjournals.org
… -induced lung fibrosis, suggesting a role for growth factors in … target ER (estrogen
receptor) expression in breast cancer … -like growth factor 1) (R&D Systems), TGF-β1 (transforming

[HTML][HTML] Transforming growth factor-β in tumour development

CB Trelford, L Dagnino… - Frontiers in Molecular …, 2022 - frontiersin.org
… survival by activating mechanistic target of rapamycin (mTOR). … Transforming growth factor
(TGFβ) signalling is tightly … adherens junctions observed in epithelial cells, whereas TWIST …

Targeting transforming growth factorreceptors in pulmonary hypertension

C Guignabert, M Humbert - European Respiratory Journal, 2021 - Eur Respiratory Soc
… that target three well-identified pathways of endothelial cell … ) and transforming growth
factor-β (TGF-β) signalling pathways … Elevated levels of plasma transforming growth factor-β1 in …

Estrogen receptor beta 1: a potential therapeutic target for female triple negative breast cancer

P Dey, A Wang, Y Ziegler, S Kumar, S Yan… - …, 2022 - academic.oup.com
… The SNAIL and SLUG (SNAI2) genes encode Snail family transcription factors that downregulate
E-… significance involving hormone responsiveness and KRAS signaling represented in …

Structure, unique biological properties, and mechanisms of action of transforming growth factor β

N Zelisko, R Lesyk, R Stoika - Bioorganic Chemistry, 2024 - Elsevier
Transforming growth factor β (TGF-β) is a ubiquitous molecule. It is a 25-kDa homodimeric
protein composed of two identical disulfide-linked 12.5-kDa polypeptide chains that are …

TGF-β1–a truly transforming growth factor in fibrosis and immunity

M Lodyga, B Hinz - Seminars in cell & developmental biology, 2020 - Elsevier
signalling (ie, depending on the signalling state of the target cell) is one reason why TGF-β1
, promotes vessel maturation and inhibits the growth and migration of epithelial cells [68]. As …

[HTML][HTML] Estrogen receptors in epithelial-mesenchymal transition of prostate cancer

E Di Zazzo, G Galasso, P Giovannelli, M Di Donato… - Cancers, 2019 - mdpi.com
… in epithelial cells from BPH specimens. Such a process, however, was correlated to abnormalities
in ER and transforming growth factor (TGF)-β signaling, … of new targets for therapeutic …

[HTML][HTML] Reprogramming of mesothelial-mesenchymal transition in chronic peritoneal diseases by estrogen receptor modulation and TGF-β1 inhibition

RB Wilson, R Archid, MA Reymond - International Journal of Molecular …, 2020 - mdpi.com
… -α receptors and block transforming growth factor-1 (TGF-β1)… the YAP target genes connective
tissue growth factor (CTGF) … the epithelial cells of PDAC, which was mediated via the cell

Aggravation of pulmonary fibrosis after knocking down the aryl hydrocarbon receptor in the insulin‐like growth factor 1 receptor pathway

SM Wu, JJ Tsai, HC Pan, JL Arbiser… - British Journal of …, 2022 - Wiley Online Library
… The AhR/IGF1R axis is a potential target for the treatment of lung injury and … transforming
growth factor beta … This study on Beas2B cells showed that BLM and TGF-β1 markedly induced …