Role of TRPV4-P2X7 pathway in neuropathic pain in rats with chronic compression of the dorsal root ganglion

X Fan, C Wang, J Han, X Ding, S Tang, L Ning - Neurochemical Research, 2021 - Springer
… As a member of the transient receptor potential vanilloid channel (TRPV) subfamily, … allodynia
in neuropathic pain. We also detected the effect of BBG on thermal hyperalgesia induced

[HTML][HTML] Spared nerve injury causes sexually dimorphic mechanical allodynia and differential gene expression in spinal cords and dorsal root ganglia in rats

FHG Ahlström, K Mätlik, H Viisanen, KJ Blomqvist… - Molecular …, 2021 - Springer
… the induction of allodynia in female rats. These cells can also infiltrate the spinal cord (SC)
following PNI and play a role in painpaw in Experiment I (Fig. 2a) at baseline prior to spared …

… and BDNF Expression in Rat Dorsal Root Ganglion with Resiniferatoxin-Induced Neuropathic Pain: Modulation by Pulsed Radiofrequency Applied to the Sciatic Nerve

T Koshida, T Maruta, N Tanaka… - Acta Medica …, 2023 - miyazaki-u.repo.nii.ac.jp
… Resiniferatoxin (RTX) is an ultrapotent agonist of transient … of the duration of mechanical
allodynia before the PRF … both contralateral and ipsilateral paw withdrawal thresholds 1 week …

[HTML][HTML] Suppression of superficial microglial activation by spinal cord stimulation attenuates neuropathic pain following sciatic nerve injury in rats

M Shinoda, S Fujita, S Sugawara, S Asano… - International Journal of …, 2020 - mdpi.com
… excitation induced by hind paw stimulation, … nerve injury leads to the production and release
of tumor necrosis factor (TNFα) in microglia in SDH [25,26]. TNFα signaling in the transient

Neuropathic pain: from mechanisms to treatment

NB Finnerup, R Kuner, TS Jensen - Physiological reviews, 2021 - journals.physiology.org
… cause can be a transient conduction nerve block (282). … -induced neuropathic allodynia and
signs of ongoing pain have … of spinal cord injury (SCI) in mice and rats are frequently used to …

[HTML][HTML] Neurodynamic treatment promotes mechanical pain modulation in sensory neurons and nerve regeneration in rats

G Carta, BE Fornasari, F Fregnan, G Ronchi… - Biomedicines, 2022 - mdpi.com
… have shown that the genes related to mechanical allodynia that we have assessed in our …
to induce a windup or temporal summation phenomenon, consisting of transiently increased …

Potential mechanisms for osteopathic manipulative treatment to alleviate migraine-like pain in female rats

K Byrd, M Lund, Y Pan, BH Chung, K Child… - Frontiers in Pain …, 2024 - frontiersin.org
… Umbellulone, identified as a transient receptor potential … to the neck muscles and cervical
vertebra of the rats before or … hind paw allodynia induced by umbellulone in CFAprimed rats. …

Suppression of neuropathic pain by selective silencing of dorsal root ganglion ectopia using nonblocking concentrations of lidocaine

SL Yatziv, M Devor - Pain, 2019 - journals.lww.com
… L5 SNL-induced tactile allodynia without blocking normal … ) to evaluate effects on hind
paw allodynia of acutely applying … lidocaine transiently eliminates tactile allodynia in rats with …

[HTML][HTML] Electroacupuncture alleviates paclitaxel-induced peripheral neuropathic pain in rats via suppressing TLR4 signaling and TRPV1 upregulation in sensory …

Y Li, C Yin, X Li, B Liu, J Wang, X Zheng… - International Journal of …, 2019 - mdpi.com
… with burning pain, tingling, numbness, and allodynia in the … in the treated hind paw compared
with rats treated with vehicle (… EA reduced the upregulation of TRPV1 (Transient Receptor …

Non‐neuronal TRPA1 encodes mechanical allodynia associated with neurogenic inflammation and partial nerve injury in rats

F De Logu, G De Siena, L Landini… - British Journal of …, 2023 - Wiley Online Library
… DRGs (combined cervical, thoracic and lumbar) were bilaterally … Thus, HPMA induced by
CGRP capsaicin or AITC in rats … in the rat hind paw elicited acute and transient nocifensor …