Ramucirumab plus erlotinib in patients with untreated, EGFR-mutated, advanced non-small-cell lung cancer (RELAY): a randomised, double-blind, placebo-controlled …

K Nakagawa, EB Garon, T Seto, M Nishio… - The Lancet …, 2019 - thelancet.com
… in EGFR-mutated metastatic non-small-cell lung cancer (NSCLC) … In preclinical studies, dual
blockade of the EGFR and VEGF … : rationale and clinical applications for non-small-cell lung

… , ramucirumab plus erlotinib versus placebo plus erlotinib in patients with untreated, epidermal growth factor receptor mutation-positive, metastatic non-small-cell lung …

E Nadal, H Horinouchi, JY Shih, K Nakagawa, M Reck… - Drug Safety, 2022 - Springer
… Briefly, RELAY was a global, double-blind, placebo-… studies because study designs and
patient populations differ. In … safety reasons but in line with contemporary clinical trials in this …

… of Ramucirumab Plus Erlotinib in Taiwanese Patients with Untreated, Epidermal Growth Factor Receptor-Mutated, Stage IV Non-small Cell Lung Cancer in the RELAY …

CH Chiu, MC Lin, YF Wei, GC Chang, WC Su… - Targeted Oncology, 2023 - Springer
… The RELAY study was a global, double-blind, placebo-… +ERL in patients with untreated
metastatic NSCLC and sensitizing … of patients with untreated EGFR mutation-positive stage IV …

RELAY subgroup analyses by EGFR Ex19del and Ex21L858R mutations for ramucirumab plus erlotinib in metastatic nonsmall cell lung cancer

…, M Reck, RELAY study investigators - … Cancer Research, 2021 - AACR
… decisions to be made on a more rational basis. … -TKI treatment, subgroup analyses of
several landmark studies in EGFRm … Briefly, RELAY is a global, double-blind, placebo-controlled, …

RELAY, ramucirumab plus erlotinib versus placebo plus erlotinib in untreated EGFR-mutated metastatic non-small cell lung cancer: exposure–response relationship

K Nakagawa, EB Garon, L Gao, S Callies… - Cancer chemotherapy …, 2022 - Springer
… such as ramucirumab is a rational treatment strategy in EGFR-mutant NSCLC. Indeed, clinical
studies have … In REVEL, a randomized, double-blind Phase 3 trial, patients with previously …

… outcomes in RELAY, a phase 3 trial of ramucirumab plus erlotinib versus placebo plus erlotinib in untreated EGFR-mutated metastatic non-small-cell lung cancer

…, K Nakagawa, RELAY investigators - … Medical Research …, 2020 - Taylor & Francis
Full article: Patient-reported outcomes in RELAY, a phase 3 trial of ramucirumab plus erlotinib
versus placebo plus erlotinib in untreated EGFR-mutated metastatic non-small-cell lung

[HTML][HTML] Ramucirumab plus erlotinib versus placebo plus erlotinib in previously untreated EGFR-mutated metastatic non-small-cell lung cancer (RELAY): exploratory …

…, K Nakagawa, RELAY study investigators - ESMO open, 2023 - Elsevier
… of patients with epidermal growth factor receptor (EGFR)-… treatment observed in RELAY,
NEJ026, and other studies for … an independent review committee identified for this purpose and …

[HTML][HTML] RELAY+: Exploratory Study of Ramucirumab Plus Gefitinib in Untreated Patients With EGFR-Mutated Metastatic NSCLC

M Nishio, K Nishio, M Reck, EB Garon… - … Clinical and Research …, 2022 - Elsevier
placebo plus erlotinib in untreated EGFR-mutated metastatic … In the Asian subset of FLAURA,
a phase 3 double-blind study … of EGFR mutation-positive non-small cell lung cancer treated

[HTML][HTML] RELAY, ramucirumab plus erlotinib (RAM+ ERL) in untreated metastatic EGFR-mutant NSCLC (EGFR+ NSCLC): association between TP53 status and …

M Nishio, L Paz-Ares, M Reck, K Nakagawa… - Clinical Lung Cancer, 2023 - Elsevier
… , metastatic, EGFR-mutated, nonsmall-cell lung cancer (… reported, 36 RELAY is a randomized,
double-blind, Placebo-… an independent review committee identified for this purpose and …

The safety and efficacy of erlotinib and ramucirumab combination in EGFR-mutant non-small-cell lung cancer

M Boussageon, A Swalduz, M Pérol - … of Anticancer Therapy, 2021 - Taylor & Francis
… a double-blind, placebo-controlled phase III trialRELAY subgroup analyses by EGFR
ex19del and ex21L858R mutations for ramucirumab plus erlotinib in metastatic non-small cell lung