… Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Metastatic Non-Small Cell Lung Cancer Patients with Poor Performance Status and Epidermal Growth …

Y Okuma, Y Shintani, I Sekine, T Shukuya… - Clinical Lung Cancer, 2024 - Elsevier
… good-PS patients with EGFR mutation-positive advanced NSCLC … or increased incidence of
erlotinib-related toxicities. … specific reasons for poor PS were not clarified in the current study. …

… benefits of first-line treatments for Asian patients with advanced epidermal growth factor receptor-mutated NSCLC harboring exon 19 deletion: a systematic review …

SK Chan, HCW Choi, VHF Lee - Cancers, 2022 - mdpi.com
Erlotinib plus bevacizumab, ramucirumab plus erlotinib, and … reported in Asia, with non-small-cell
lung cancer (NSCLC) as … out a well-designed phase III, multicenter RCT, which makes …

Epidermal growth factor receptor-targeted therapy for the treatment of non-small cell lung cancer: a review of phase II and III trials

HL Lu, GL Jie, YL Wu - Expert Opinion on Emerging Drugs, 2022 - Taylor & Francis
… of erlotinib as a first-line treatment for EGFR mutation-positive … of ramucirumab plus erlotinib
with that of erlotinib alone in … is a multicenter, randomized, double-blind, phase 3 clinical trial

Erlotinib and bevacizumab in elderly patients≥ 75 years old with non-small cell lung cancer harboring epidermal growth factor receptor mutations

Y Aoshima, M Karayama, N Inui, H Yasui… - Investigational New …, 2021 - Springer
… , six patients had previously treated stable brain metastases. … in elderly patients with
EGFR mutation-positive NSCLC. The … plus gefitinib, or erlotinib plus ramucirumab [25,26,27,28,29]. …

[HTML][HTML] Epidermal growth factor receptor first generation tyrosine-kinase inhibitors

A Martinez-Marti, A Navarro, E Felip - … Lung Cancer Research, 2019 - ncbi.nlm.nih.gov
… first-line erlotinib in Asian population with EGFR mutation-positiveRELAY trial is a phase
III double-blind study that assessed the role of ramucirumab or placebo in addition to erlotinib

… Epidermal Growth Factor Receptor Inhibitors Plus Antiangiogenic Drugs Versus Third-Generation Epidermal Growth Factor Receptor Inhibitors in Advanced Non …

M Mosca, N Conci, A Di Federico, V Tateo… - JCO Precision …, 2023 - ascopubs.org
… ) or (VEGF inhibitor or bevacizumab or ramucirumab or VEGFR inhibitor or anti-… metastatic
EGFR mutation-positive non-small-cell lung cancer (FURLONG): A multicentre, double-blind

Study design and rationale for the PACE-LUNG trial: a multicenter, single-arm, phase II clinical trial evaluating the efficacy of additional chemotherapy for patients with …

F Acker, L Aguinarte, F Althoff, S Heinzen, M Rost… - Clinical lung cancer, 2022 - Elsevier
… , treatment of advanced or metastatic non-small cell lung … with the first- or second-generation
TKI erlotinib, gefitinib or … as bevacizumab (NCT04181060) or ramucirumab 19 in this setting, …

[PDF][PDF] A Patient With Newly Diagnosed, Advanced EGFR-Mutated NonSmall Cell Lung Cancer

L Lara-Mejía, R Sánchez-Reyes… - Oncology (Williston …, 2020 - researchgate.net
… of erlotinib and ramucirumab versus erlotinib alone in the … Patients with brain metastases
were excluded from the study. … mutation-positive NSCLC who received sequential treatment

Novel systemic therapies in the management of tyrosine kinase inhibitor-pretreated patients with epidermal growth factor receptor-mutant non-small-cell lung cancer

YS Li, GL Jie, YL Wu - Therapeutic Advances in Medical …, 2023 - journals.sagepub.com
… the feasibility of combining erlotinib and angiogenesis for … pretreated patients with EGFR
mutation-positive lung cancer was … This study is currently enrolling patients with metastatic EGFR…

[HTML][HTML] Dual EGFR-VEGF pathway inhibition: a promising strategy for patients with EGFR-mutant NSCLC

X Le, M Nilsson, J Goldman, M Reck… - Journal of Thoracic …, 2021 - Elsevier
RELAY trial, a large global, placebo-controlled, double-blind trial, evaluated the effects of
erlotinib plus ramucirumab versus erlotinib plus placebo in 449 patients with metastatic NSCLC…