Optimizing outcomes and treatment sequences in EGFR mutation-positive non-small-cell lung cancer: recent updates

N Girard - Future Oncology, 2019 - Taylor & Francis
… III RELAY study have demonstrated superior PFS with erlotinib … the inclusion of patients with
stable brain metastases whereas … half the patients treated with erlotinib plus ramucirumab. …

Therapeutic advances in nonsmall cell lung cancer: Focus on clinical development of targeted therapy and immunotherapy

Y Cheng, T Zhang, Q Xu - MedComm, 2021 - Wiley Online Library
trial in China, a double-blind, head-to-head phase III study … T790M mutation-positive
advanced NSCLC patients treated with … Ramucirumab in combination with erlotinib significantly …

The different overall survival between single-agent EGFR-TKI treatment and with bevacizumab in non-small cell lung cancer patients with brain metastasis

TH Chiu, PH Tung, CH Huang, JS Ju, ACC Huang… - Scientific Reports, 2022 - nature.com
patients, have demonstrated PFS benefit of erlotinib plus … On the other side, treatment of
osimertinib plus ramucirumab … This has been observed in the NEJ 026 and RELAY studies in …

Angiogenesis inhibition in non-small cell lung cancer: a critical appraisal, basic concepts and updates from American Society for Clinical Oncology 2019

AR Cantelmo, C Dejos, F Kocher, W Hilbe… - Current Opinion in …, 2020 - journals.lww.com
… to daily erlotinib with ramucirumab, or erlotinib with placebo. … for the treatment of patients
with locally advanced, metastatic or … combination with erlotinib alone in EGFR mutation positive

An updated network meta-analysis of EGFR-TKIs and combination therapy in the first-line treatment of advanced EGFR mutation positive non-small cell lung cancer

Y Qi, X Xia, L Shao, L Guo, Y Dong, J Tian, L Xu… - Frontiers in …, 2022 - frontiersin.org
… They were ranked the top two treatments for patients with brain metastasis. Better … erlotinib
and ramucirumab showed a significantly improved PFS of 19.4 months in the RELAY trial

[HTML][HTML] Real-world experience of afatinib as first-line therapy for advanced EGFR mutation-positive non-small cell lung cancer in Korea

SY Lee, CM Choi, YS Chang, KY Lee… - … lung cancer Research, 2021 - ncbi.nlm.nih.gov
… This was a retrospective, multicenter cohort study of patientspatients with baseline brain
metastases no longer had brain … , such as erlotinib plus either ramucirumab or bevacizumab, …

Long-term progression-free survival in non-small cell lung cancer patients: a spotlight on bevacizumab and its biosimilars

F Seiwerth, L Bitar, M Samaržija… - … on Biological Therapy, 2024 - Taylor & Francis
… of treatment of metastatic NSCLC, as well small-cell lung … received either nivolumab or
placebo and the median OS was … Ramucirumab in combination with erlotinib showed a slightly …

Stereotactic ablative radiotherapy for acquired resistance to EGFR therapy in metastatic non-small cell lung cancer

R Chicas-Sett, J Castilla Martinez… - Frontiers in …, 2023 - frontiersin.org
… in 16% of patients versus 13% in the placebo group (16). … such as erlotinib plus ramucirumab
or erlotinib plus bevacizumab have … II multicenter study has analyzed toxicity in 381 patients

… status in combination treatment with EGFR tyrosine kinase inhibitors and anti-angiogenic agents in advanced non-small cell lung cancer harboring susceptible EGFR …

TH Lee, HL Chen, HM Chang, CM Wu, KL Wu… - Journal of Clinical …, 2022 - mdpi.com
… 3 RELAY trial was designed to compare ramucirumab plus erlotinib and erlotinib alone and
ramucirumab plus erlotinib showed superior PFS in patients with EGFR-mutated metastatic

Therapy for stage IV nonsmall-cell lung cancer with driver alterations: ASCO and OH (CCO) joint guideline update

NH Hanna, AG Robinson, S Temin… - Journal of Clinical …, 2021 - ascopubs.org
… plus ramucirumab versus erlotinib plus placebo 19 … with BRAF V600 mutationpositive NSCLC,
the primary outcome, … or metastatic tumors who had previous treatment with therapy other …