… deficits in MDD. To do this, we aimed to establish how well cognitive dysfunction has been
… effects standard and experimental treatments have on cognitive deficits. Our ultimate goal is …

… cognitive impairment in elderly individuals with moderate-to-severe depression is a strong
predictor of dementia… Citation 35 Preclinical studies suggest that simultaneous stimulation of 5-…

… in the treatment of cognitive dysfunction in mood disorders [Citation87]. In pre-clinical studies…
discussed in this review, and the need to target the cognitive dysfunction observed in MDD, …

… dysfunction in major depressive disorder – A review of the preclinical evidence for efficacy
of selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors and …

… Cognitive impairment is a core feature of major depressive disorder (MDD), broadly
characterised by heterogeneous … Although cognitive impairment occurs in most clinical cases of …

… The aim of this review is to describe the clinical neuropsychological profile in MDD and how
… decade on cognitive deficits in MDD from a state, trait, and scar perspective. This review, …

… Methods: We conducted a review of key data obtained from preclinical behavioral models
and … could be a useful option to treat cognitive dysfunction in depressed patients, as a first-line …

… We will review the proposed cellular mechanisms underlying the pathogenesis of POCD
in pre-clinical and human studies. We will present the evidence underlying the debate on the …

… of any observed effect of severe depression on cognitive function. Although our participants
… , 38 severe systemic and psychiatric illnesses are known to influence mood, cognition, and …

… approved for the treatment of major depressive disorder (MDD… Areas covered: This review
focuses on the preclinical and … in treating depressive symptoms and cognitive deficits in MDD …