FDA approval summary: idecabtagene vicleucel for relapsed or refractory multiple myeloma

P Sharma, B Kanapuru, B George, X Lin, Z Xu… - Clinical Cancer …, 2022 - AACR
… )] in adults with relapsed and refractory multiple myeloma, with a primary efficacy endpoint
of ORR per independent response committee (IRC) based on International Myeloma Working …

Current treatment approaches to newly diagnosed multiple myeloma

S Ghandili, KC Weisel, C Bokemeyer… - … Research and Treatment, 2021 - karger.com
… : Multiple myeloma is a so far incurable malignant plasma cell disorder. During the past 2
decades, treat… in relapsed or refractory multiple myeloma. Blood. 2019 Aug 22;134(8):668–77. …

[HTML][HTML] Treatment patterns and outcomes in triple-class exposed patients with relapsed and refractory multiple myeloma: findings from the multinational ITEMISE …

S Dhanasiri, G Hollier-Hann, C Stothard, DS Dhanda… - Clinical …, 2021 - Elsevier
… Patients with relapsed and refractory multiple myeloma (RRMM) have a poor prognosis and
limited treatment options after exposure to an immunomodulatory drug, proteasome inhibitor …

Idecabtagene vicleucel (ide-cel) CAR T-cell therapy for relapsed and refractory multiple myeloma

LD Anderson Jr - Future Oncology, 2021 - Taylor & Francis
… receptor (CAR) T-cell therapy targeting B-cell … relapsed and refractory multiple myeloma
(RRMM) after multicenter trials have demonstrated unprecedented results in this difficult-to-treat

Treatment of relapsed/refractory multiple myeloma in the bortezomib and lenalidomide era: A systematic review and network meta-analysis

LJ Arcuri, AD Americo - Annals of hematology, 2021 - Springer
… prioritizing some treatments that are more effective than others in patients with relapsed/refractory
multiple myeloma. We hope this study will help centers to optimize treatment selection …

[HTML][HTML] Idecabtagene vicleucel (ide-cel, bb2121) in relapsed and refractory multiple myeloma: analyses of high-risk subgroups in the KarMMa study

NS Raje, DS Siegel, S Jagannath, S Lonial, NC Munshi… - Blood, 2020 - Elsevier
… Background: Outcomes remain poor in patients with high-risk relapsed and refractory multiple
myeloma (RRMM) receiving conventional treatments, including immunomodulatory drugs (…

Real-world outcomes and factors impacting treatment choice in relapsed and/or refractory multiple myeloma (RRMM): a comparison of VRd, KRd, and IRd

A Chari, PG Richardson, D Romanus… - Expert Review of …, 2020 - Taylor & Francis
… Rd in a large phase 3 study in frontline treatment (SWOG S0777), in the relapsed/refractory
multiple myeloma (RRMM) setting, only single-arm phase 2 data have been published, …

A comparison of the efficacy of immunomodulatory-free regimens in relapsed or refractory multiple myeloma: a network meta-analysis

K Weisel, P Sonneveld, A Spencer, M Beksac… - Leukemia & …, 2019 - Taylor & Francis
Treatment history influences the outcomes of subsequent therapies in … with relapsed or
refractory multiple myeloma (RRMM) and needs to be considered when deciding which treatment

Current management and emerging treatment strategies for multiple myeloma

M Lei, EB Kim, A Branagan, U Lou, M Zemel… - Rinsho Ketsueki, 2019 - jstage.jst.go.jp
… 2 Treatment schema for relapsed refractory multiple myeloma and commonly used
regimens. ASCT, autologous stem cell transplant; Bort, bortezomib; Carfil, carfilzomib; DPd, …

Cilta-cel or standard care in lenalidomide-refractory multiple myeloma

J San-Miguel, B Dhakal, K Yong… - … England Journal of …, 2023 - Mass Medical Soc
… -cell therapy, is effective in heavily pretreated patients … relapsed or refractory multiple
myeloma. We investigated cilta-cel in earlier treatment lines in patients with lenalidomide-refractory