Paradigms for investigating invasive trophoblast cell development and contributions to uterine spiral artery remodeling

KM Varberg, MJ Soares - Placenta, 2021 - Elsevier
… In humans, trophoblast cells plug uterine spiral arteries until … is dynamic and an important
factor affecting hemodynamics … cells affect uterine spiral artery remodeling and trophoblast cell …

Mechanical forces on trophoblast motility and its potential role in spiral artery remodeling during pregnancy

B Xie, H Wu, J Li, X Lv, Y Zhou, Q Yu, S Cui, L Zeng… - Placenta, 2022 - Elsevier
… of trophoblast plugs and their haemodynamic consequences … of haemodynamic forces in
placental vascular remodeling, … fluid SS in human utero-placental circulation have been applied…

From stem cells to spiral arteries: A journey through early placental development

JL James, AL Boss, C Sun, HH Allerkamp, AR Clark - Placenta, 2022 - Elsevier
… and spiral artery remodelling, and finally remodelling of the … the SAs, endoarterial trophoblasts
form significant ‘plugs’ of up to … that can influence both SA remodelling and utero-placental

… new: digital quantification of uterine vascular remodelling and trophoblast plugging in historical collections provides new insight into adaptation of the utero-placental …

HH Allerkamp, AR Clark, TC Lee… - Human …, 2021 - academic.oup.com
… of trophoblast plugs suggest that they will impact on the … the spiral arteries (SAs), adopt an
endovascular trophoblast (EndTb) … that plugs also regulate upstream SA haemodynamics, and …

Understanding the uterine artery Doppler waveform and its relationship to spiral artery remodelling

C Lloyd-Davies, SL Collins, GJ Burton - Placenta, 2021 - Elsevier
… a reflection of trophoblast-induced spiral artery remodelling is … waveform changes as a
purely haemodynamic phenomenon. … potential causes within the utero-placental vasculature …

Hemodynamic consequences of incomplete uterine spiral artery transformation in human pregnancy, with implications for placental dysfunction and preeclampsia

M Zamir, DM Nelson, Y Ginosar - Journal of Applied …, 2021 - journals.physiology.org
… The “depth” of trophoblast-mediated spiral artery remodeling … state of hemodynamics at
different degrees of spiral artery … completely occlude spiral artery blood flow—these plugs

Estrogen actions in placental vascular morphogenesis and spiral artery remodeling: A comparative view between Humans and Mice

M Rusidzé, A Gargaros, C Fébrissy, C Dubucs, A Weyl… - Cells, 2023 - mdpi.com
… actions during utero-placental vascular morphogenesis, … control of trophoblast behavior,
spiral artery remodeling, and … utero-placental vascular morphogenesis and hemodynamics from …

Unraveling the mysteries of spiral artery remodeling

L Zhang, J Liu, X Feng, GE Lash - Placenta, 2023 - Elsevier
… extravillous trophoblast (eEVT) invasion of spiral arteries in … This suggests that the trophoblast
plugs in the vessels early … influence on the uterine artery waveform than the degree of …

Establishment of maternal blood supply to the placenta: insights into plugging, unplugging and trophoblast behaviour from an agent-based model

R Saghian, G Bogle, JL James… - Interface Focus, 2019 - royalsocietypublishing.org
… of spiral artery remodelling. Prior to trophoblast mediated remodelling the spiral arteries are
… also have important upstream haemodynamic consequences that are likely to influence SA …

Spiral, uterine artery doppler and placental ultrasound in relation to preeclampsia

T de Ganzo Suárez, C de Paco Matallana… - Best Practice & …, 2023 - Elsevier
trophoblast cells. This process and changes in the spiral arteries are called spiral artery
remodeling. … 8 and 12 and will affect the decidual portion of the spiral arteries. The activity of the …