… Most anti-cancer therapies to date have been designed to interfere with … for tumor growth
and progression. Traditional cytotoxic chemotherapies usually target rapidly proliferating cancer …

… of cancer cells and, meanwhile, provide multiple targets of … the agents targeting TAMs for
cancer therapy. It is hoped that … in clinic therapeutic applications against tumor progression. …

… enhances TCF targets with increase in cell growth, differentiation, … treatment of CRC to further
identify novel therapeutic targets. … ) targets will be the future avenue for efficient treatment of …

… deviate from normal differentiation and pathologically activated… antitumor immunity and
promote tumor progression. For one … support tumor progression and induce antitumoral therapy …

… cells, and mediates tumor growth either through stimulating … , is essential for osteoblast
differentiation and bone formation … ,64], which promotes the differentiation of pre-osteoblasts into …

… the histology, and hence the differentiation trajectory, of the tumor of origin 39 . However, …
metastatic tumor growth, which may in turn be potential targets for therapeutic intervention: …

… breast cancer cell line via the activation of ERα target genes (… It was observed that in
differentiated human colon tumors … CYP27B1 mRNA during early tumor progression. This …

… promising cancer immunotherapeutic targets. Targeting the … These antigens are important
for the differentiation of cancer … experienced disease progression after DC-vaccination therapy …

… of which differential effects of ROS are reported in tumor cells. In a … as a therapeutic target
to inhibit tumor growth via impeding … To develop an effective anti-tumor treatment modality, the …

… of ncRNAs in cancer progression emphasizes the potential of ncRNAs for cancer treatment.
… also shown potential as therapeutic targets because of their differential expression patterns …