… defined by tumor-suppressive functions like inhibition of cell … of PANX1 in C6 glioma cells
resulted in tumor suppresion139… of calcium permeability of the channel formed by pannexin 1. …

… Interestingly, Px1-transfected C6 glioma cells in culture showed reduced proliferation and
… C6 cells (Lai et al., 2007). When inoculated to nude mice, Px1-transfected C6 glioma cells …

… of the tumor microenvironment (TME), including immune cells… pannexins facilitate, or in some
cases inhibit, tumor cell growth … Tumor-suppressive effects of pannexin 1 in C6 glioma cells. …

… in human glioma cell lines. However, the authors also found that rat C6 glioma cells lacked
… reduction in several cancerous properties of the rat cells, as well as increased gap junction …

… C6 glioma cells; this was associated with increased and decreased Cx43 phosphorylation,
respectively (434). Moreover, TGF-β3 decreased coupling of cortical and striatal, but not …

… The occurrence of intercellular channels formed by pannexin1 has been challenged for …
exogenous human pannexin1 (hPanx1) cell–cell channels expressed in HeLa cells knocked out …

… of Panx-1 in C6 glioma cells reduces their proliferative and migratory capability. When
Panx-1 overexpressed cells were … Tumor-suppressive effects of pannexin 1 in C6 glioma cells …

… The large pore ion channel pannexin 1 (Panx1) has also been implicated in gut dysfunction.
… In this respect, it is worth noting that C6 glioma cells do not express Panx1 42 , but can …

… for C6 cells motility, which are derived from rat glia. Indeed, overexpression of PANX1 reduces
C6 glioma cell … of CX43, which has a tumor suppressive role in rhabdomyosarcoma (121). …

… cells following exposure to ionizing radiation [130]. In this regard, transfecting C6 glioma cells
with … cells, leading to an enhanced therapeutic effect in vivo [[131], [132], [133]]. The same …