… Eleven previously undescribed alkaloids, named sinometumines AK, along with three known
alkaloids, were isolated from the rhizomes of Sinomenium acutum. The chemical structures …

… to sinomenine (10) [15], a morphinane alkaloid. Compared with 10, the significant downfield
… sinomenine indicated that 1 was a symmetrical dimer of morphinane alkaloid, similar to (S)-…

… stems and rhizomes of Sinomenium acutum, two new aporphine analogues, acutumalkaloids
… alkaloids such as morphinane-type [2], aporphine-type [3], and berberine-type alkaloids [4] …

… , aporphine, morphinane, and other skeleton alkaloids. The acquisition … the morphine alkaloid
pathway in the isoquinoline alkaloid … KEGG of Sinomenium acutum, but no morphine or its …

… The above data speculated that compound 1 was a modified morphinane alkaloid. The
similarity between the 1D-NMR data of compound 1 and dauricumidine 6 indicated that two …

… )-reticuline to yield the promorphinan alkaloid salutaridine. As sinomenine is also a member
of the morphinan alkaloid with a different bridge from morphine, thebaine, and codeine, one …

… been carried out on CH 2 Cl 2 extract of Alphonsea cylindrica leaves, resulting in the isolation
of three new morphinan alkaloids. They are kinomenine (1), N-methylkinomenine (2), and …

… an alkaloid, found in the roots of the Sinomenium acutum, which is a popular Chinese medicinal
plant. It contains alkaloids… It is a morphinan derivative which is related to opioids such as …

… 1), and a new naturally occurring cularine alkaloid (S)-2, 3, 12… [2, 3, 4-ij]isoquinoline (5),
along with four known alkaloids … the number of alkaloids with morphinan or cularine scaffold, …

… Alkaloids, the principal constituents in the caulis of Sinomenium acutum, have gained an …
Unlike morphine, morphinan alkaloids do not have a furan nucleus at C4 and C5, which …