Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics

S Qin, W Xiao, C Zhou, Q Pu, X Deng, L Lan… - Signal transduction and …, 2022 - nature.com
… to improve our understanding of P. aeruginosa pathogenesis and host defense. Nevertheless,
… and the slow development of effective antimicrobials present daunting challenges and …

Cystic fibrosis and Pseudomonas aeruginosa: the host-microbe interface

S Malhotra, D Hayes Jr, DJ Wozniak - Clinical microbiology …, 2019 - Am Soc Microbiol
… In an effort to review our current understanding of the host-… at the interface of host-pathogen
interactions. Broadly, deficits … membranes), thereby explaining broad efficacy against Gram-…

Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

I Jurado-Martín, M Sainz-Mejías… - International journal of …, 2021 - mdpi.com
aeruginosahost interactions are still poorly understood, complicating the development of
effective … , is also key to understanding the pathoadaptability of this pathogen, especially with …

[HTML][HTML] Emerging therapies against infections with Pseudomonas aeruginosa

B Tümmler - F1000Research, 2019 - ncbi.nlm.nih.gov
… the tolerability and efficacy of a cocktail of lytic anti- P. … target the Pseudomonas bacteria in
the individual host habitat … we need an in-depth understanding of how the mutual evolutionary …

Pathogenesis of the Pseudomonas aeruginosa Biofilm: A Review

FF Tuon, LR Dantas, PH Suss, VS Tasca Ribeiro - Pathogens, 2022 - mdpi.com
… , making it an interesting in vitro model to understand biofilm formation [18]. … that phage
therapy is an effective approach for destroying P. … It is important to elucidate the interaction of P. …

The Epidemiology and Pathogenesis and Treatment of Pseudomonas aeruginosa Infections: An Update

D Reynolds, M Kollef - Drugs, 2021 - Springer
aeruginosa have been shown to be efficacious in the … step for infection and is accomplished
by interactions between … CF patients is often similar and understanding the treatment of a CF …

Immune Responses to Pseudomonas aeruginosa Biofilm Infections

C Moser, PØ Jensen, K Thomsen, M Kolpen… - Frontiers in …, 2021 - frontiersin.org
… In the present review we describe our current understanding of … The present review is focused
on interactions between P. … new and effective treatments against biofilm-based infections. …

Urinary tract infections: microbial pathogenesis, host–pathogen interactions and new treatment strategies

RD Klein, SJ Hultgren - Nature Reviews Microbiology, 2020 - nature.com
… together with our increasing understanding of the detrimental … resolve in the absence of
effective antibiotic treatment, and … with pyochelin iron uptake in Pseudomonas aeruginosa 79 . …

Pseudomonas aeruginosa and microbial keratitis

Y Hilliam, S Kaye, C Winstanley - Journal of medical …, 2020 - microbiologyresearch.org
… but understanding the genetic differences that predispose P. … more effective future treatments
to reduce the morbidity of P. … There is evidence that both the PQS and IQS systems interact

It's Not Easy Being Green: A Narrative Review on the Microbiology, Virulence and Therapeutic Prospects of Multidrug-Resistant Pseudomonas aeruginosa

P Behzadi, Z Baráth, M Gajdács - Antibiotics, 2021 - mdpi.com
… A possible explanation was that the genomic island carrying … by the mucoid variants are
effective in scavenging ROS, … facilitates its own uptake by interacting with the Gram-negative LPS …