[HTML][HTML] The mysteries of capsaicin-sensitive afferents

MJM Fischer, CI Ciotu, A Szallasi - Frontiers in Physiology, 2020 - frontiersin.org
capsaicin desensitization has a clear therapeutic potential to relieve pain, but has also
mysterious … In conclusion, capsaicin has been an invaluable tool in sensory pharmacology to …

[HTML][HTML] Pharmacological activity of capsaicin: Mechanisms and controversies

W Zhang, Y Zhang, J Fan… - Molecular Medicine …, 2024 - spandidos-publications.com
capsaicin as an 8% dermal analgesic patch (640 mcg/cm2, total dose 179 mg), while lower
doses do not relieve pain … for enhancing the clinical utility of capsaicin-based treatments. …

Capsaicin

A Waheed, L Arshad, S Tabassum, I Zahid… - A Centum of Valuable …, 2021 - Elsevier
… creams having capsaicin are used to treat different pains and have analgesic effects to cure
… Some pieces of evidence suggest that it is used to treat severe pain in patients who do not …

Novel agents in neuropathic pain, the role of capsaicin: pharmacology, efficacy, side effects, different preparations

OM Hall, A Broussard, T Range… - Current pain and …, 2020 - Springer
… These results support the promising future for utility of capsaicin as an early, first-line
treatment of neuropathic pain to improve quality of life and reduce refractory chronic pain which …

Flavor mystery of spicy hot pot base: Chemical understanding of pungent, numbing, umami and fragrant characteristics

B Wang, W Wu, J Liu, OP Soladoye, CT Ho… - Trends in Food Science …, 2023 - Elsevier
… bases is considered a pleasurable pain. The málà provides … that sucralose can reduce the
pungency of capsaicin in the … and informative sensory evaluation tool. It has been applied in …

Novel TRPV1 modulators with reduced pungency induce analgesic effects in mice

A Treat, V Henri, J Liu, J Shen, M Gil-Silva… - ACS …, 2022 - ACS Publications
… Our results demonstrate that male and female mice treated with YB capsaicin analogues
showed diminished pain-associated behavior in the spontaneous formalin assay as well as …

[HTML][HTML] Injectable capsaicin for the management of pain due to osteoarthritis

JN Campbell, R Stevens, P Hanson, J Connolly… - Molecules, 2021 - mdpi.com
… , addresses pain from abnormal nociceptor activity in the … for using capsaicin by injection
for painful conditions such as … , through genetic tools, eliminates the pungency of capsaicin, …

Exploring Capsaicin-Based Drug Delivery Systems for Cancer Treatment: A Review

D SR Khafaga, EF Ewies - Egyptian Journal of Chemistry, 2023 - journals.ekb.eg
… to fully understand the potential of capsaicin-based delivery systems for cancer treatment. …
and is being investigated as a potential long-term permanent pain reduction pathway [22]. …

Capsaicin-the DOOuble Agen7.

P Taneja - SAAD Digest, 2019 - search.ebscohost.com
… and pharmacokinetic properties of capsaicin that allow for its dual use in the creation of
pain (for its use in … capsaicin's use as a tool in human and animal studies.32 Symptoms from …

Capsaicin 8% dermal patch in clinical practice: an expert opinion

C Bonezzi, A Costantini, G Cruccu… - Expert opinion on …, 2020 - Taylor & Francis
… Topical capsaicin acts locally, and pain relief is not facilitated … The median time-to-onset of
pain relief was shorter for capsaicin … , treatment satisfaction was greater with the capsaicin 8% …