[HTML][HTML] Disentangling ERBB signaling in breast cancer subtypes—A model-based analysis
S Kemmer, M Berdiel-Acer, E Reinz, J Sonntag… - Cancers, 2022 - mdpi.com
… the ERBB signaling network … the ERBB signaling network as displayed in Figure 2. Reaction
kinetics were modeled by the law of mass-action according to chemical reaction network …
kinetics were modeled by the law of mass-action according to chemical reaction network …
[HTML][HTML] The ErbB signaling network and its potential role in endometrial cancer
G Androutsopoulos, I Styliara, E Zarogianni, N Lazurko… - Epigenomes, 2023 - mdpi.com
… Some of these pathways are part of the EGF system signaling network, which becomes …
Our aim is to provide an update on current knowledge of the signaling network of ErbB …
Our aim is to provide an update on current knowledge of the signaling network of ErbB …
[PDF][PDF] Disentangling ERBB Signaling in Breast Cancer Subtypes—A Model-Based Analysis. Cancers 2022, 14, 2379
S Kemmer, M Berdiel-Acer, E Reinz, J Sonntag… - 2022 - academia.edu
… the ERBB signaling network … the ERBB signaling network as displayed in Figure 2. Reaction
kinetics were modeled by the law of mass-action according to chemical reaction network …
kinetics were modeled by the law of mass-action according to chemical reaction network …
[HTML][HTML] Homo-and heteroassociations drive activation of ErbB3
… Dimerization or the formation of higher-order oligomers is required for the activation of ErbB
receptor … Untangling the ErbB signalling network. … Untangling the ErbB signalling network. …
receptor … Untangling the ErbB signalling network. … Untangling the ErbB signalling network. …
Growth factor–dependent ErbB vesicular dynamics couple receptor signaling to spatially and functionally distinct Erk pools
Y Brüggemann, LS Karajannis, A Stanoev… - … Signaling, 2021 - science.org
… The ErbB signaling network coordinates fundamental, often opposing cellular responses,
such as proliferation and differentiation, and thus functions as important context-dependent …
such as proliferation and differentiation, and thus functions as important context-dependent …
Antitumour immunity regulated by aberrant ERBB family signalling
S Kumagai, S Koyama, H Nishikawa - Nature Reviews Cancer, 2021 - nature.com
… Oncogenic alterations of genes encoding members of the ERBB family, leading to aberrant
ERBB signalling and driving tumour growth, have been reported in various types of cancer …
ERBB signalling and driving tumour growth, have been reported in various types of cancer …
[HTML][HTML] Origin of diverse phosphorylation patterns in the ERBB system
T Okada, H Miyagi, Y Sako, M Hiroshima… - Biophysical Journal, 2022 - cell.com
… Untangling the ErbB signalling network. … phosphorylation levels influence the downstream
signaling. To understand the role of the ERBB network in signaling pathways totally, we need …
signaling. To understand the role of the ERBB network in signaling pathways totally, we need …
Unraveling ERBB network dynamics upon betacellulin signaling in pancreatic ductal adenocarcinoma in mice
K Hedegger, H Algül, M Lesina, A Blutke… - Molecular …, 2020 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) will soon belong to the top three cancer killers.
The only approved specific PDAC therapy targets the epidermal growth factor receptor (EGFR…
The only approved specific PDAC therapy targets the epidermal growth factor receptor (EGFR…
[HTML][HTML] Expanding the Disorder-Function Paradigm in the C-Terminal Tails of Erbbs
L Pinet, N Assrir, C van Heijenoort - Biomolecules, 2021 - mdpi.com
… IDRs were also shown to be important for kinase regulation in signaling networks [95]. Even
though mutations in the CT of ErbBs are much less commonly linked to disease compared to …
though mutations in the CT of ErbBs are much less commonly linked to disease compared to …
[HTML][HTML] Insights on the functional interaction between group 1 metabotropic glutamate receptors (mGluRI) and ErbB receptors
A Ledonne, NB Mercuri - International journal of molecular sciences, 2020 - mdpi.com
… Available evidence suggests that mGluRI activity is tightly dependent on ErbB signaling,
and that ErbB’s modulation profoundly influences mGluRI-dependent effects on …
and that ErbB’s modulation profoundly influences mGluRI-dependent effects on …