Evidence of the reduced abundance of proline cis conformation in protein poly proline tracts
A Urbanek, M Popovic, CA Elena-Real… - Journal of the …, 2020 - ACS Publications
… Proline is unique among the 20 genetically coded amino acids. (1) The … structures known
as poly proline helices of type-I (all-cis right handed, PP-I) or type-II (all-trans left handed, PP-II), …
as poly proline helices of type-I (all-cis right handed, PP-I) or type-II (all-trans left handed, PP-II), …
Effect of residue insertion on the stability of polyproline‐I and II structures: Circular dichroism spectroscopic analyses of block‐type oligo‐prolines (Pro) m‐Gly/Ala‐(Pro …
S Kakinoki, M Kitamura, Y Noguchi, Y Arichi - Peptide Science, 2020 - Wiley Online Library
… unique conformational behaviors. First, it is known that oligo- and poly-(l-proline) form two
unique helices, named polyproline… charge-dipole interaction in the compact structure of PP-I. …
unique helices, named polyproline… charge-dipole interaction in the compact structure of PP-I. …
Glycine in water favors the polyproline II state
… non-local interactions within compact or globular conformations or … state rather than the
secondary structure of the entire or a … ensembles of glycine residues are rare. Graf et al. explored …
secondary structure of the entire or a … ensembles of glycine residues are rare. Graf et al. explored …
[PDF][PDF] Recent advances on PolyProline II
JC Gelly, AG de Brevern - academia.edu
… structure of an oligoproline adopting an all-trans polyproline … This unique property is a reason
for PPII conformation to … The compactness and inherent flexibility of the PPII conformation is …
for PPII conformation to … The compactness and inherent flexibility of the PPII conformation is …
Copper (II)-binding induces a unique polyproline type II helical structure within the ion-binding segment in the intrinsically disordered F-domain of ecdysteroid receptor …
M Rowińska-Żyrek, A Wiȩch, J Wa̧tły… - Inorganic …, 2019 - ACS Publications
… structural and thermodynamic properties of Zn 2+ - and Cu 2+ -complexes with the AaFEcR
domain, based on peptide models of its two … structure, but result in protein compaction. (6) …
domain, based on peptide models of its two … structure, but result in protein compaction. (6) …
Deciphering the Backbone Noncovalent Interactions that Stabilize Polyproline II Conformation and Reduce cis Proline Abundance in Polyproline Tracts
B Sahariah, BK Sarma - The Journal of Physical Chemistry B, 2021 - ACS Publications
… such as trifluoroethanol but prefers a more compact right-handed PPI helical geometry in
less-… were unique PPII helical chains of different lengths (Figure 5A). The structural parameters …
less-… were unique PPII helical chains of different lengths (Figure 5A). The structural parameters …
Not Only Expansion: Proline Content and Density Also Induce Disordered Protein Conformation Compaction
… associated with the unique three-dimensional structure of folded … formation of alternative
local structural elements. In particular… secondary structural elements referred to as polyproline II (…
local structural elements. In particular… secondary structural elements referred to as polyproline II (…
Triglycine (GGG) Adopts a Polyproline II (pPII) Conformation in Its Hydrated Crystal Form: Revealing the Role of Water in Peptide Crystallization
M Guo, I Rosbottom, L Zhou, CW Yong… - The Journal of …, 2021 - ACS Publications
… The anhydrous triglycine structure was found to have two … similar environments in other crystal
structures. The O8 is one … conformation of triglycine is a compact conformation, rather than …
structures. The O8 is one … conformation of triglycine is a compact conformation, rather than …
Remarkably high solvatochromism in the circular dichroism spectra of the polyproline-II conformation: limitations or new opportunities?
… An oligomeric proline forms two types of helices, compact polyproline-I and extended … of
the P II helical structure to changing media. The use of oligo-Oic provides a unique opportunity, …
the P II helical structure to changing media. The use of oligo-Oic provides a unique opportunity, …
The ambivalent role of proline residues in an intrinsically disordered protein: from disorder promoters to compaction facilitators
B Mateos, C Conrad-Billroth, M Schiavina… - Journal of molecular …, 2020 - Elsevier
… Nuclear magnetic resonance (NMR) is a unique tool to characterize the structure and
dynamics of proteins at atomic resolution. Most methods used in the study of biomolecules rely on …
dynamics of proteins at atomic resolution. Most methods used in the study of biomolecules rely on …