Hyperuricemia and gout increased the risk of long-term mortality in patients with heart failure: insights from the National Health and Nutrition Examination Survey

Y Han, Y Cao, X Han, H Di, Y Yin, J Wu… - Journal of Translational …, 2023 - Springer
… Serum uric acid (SUA) is the ultimate product of purine metabolism, which is mainly synthesized
in the liver and excreted via the renal tract and intestines [1, 2]. Humans are exposed to …

Serum uric acid and outcome in hospitalized elderly patients with chronic heart failure through the whole spectrum of ejection fraction phenotypes

W Yan, HY Tang, YQ Yang, KL He - BMC Cardiovascular Disorders, 2023 - Springer
… with poor outcome in patients with heart failure (HF). Uric acid is associated with inflammation
… Serum uric acid (SUA), the end product of purine metabolism, has shown prognostic value …

Uric acid is a biomarker for heart failure, but not therapeutic target: result from a comprehensive meta‐analysis

S Qin, M Xiang, L Gao, X Cheng, D Zhang - ESC Heart Failure, 2024 - Wiley Online Library
… on uric acid-lowering therapy for patients with heart failure, 10 of which were traditional …
Uric acid and survival in chronic heart failure: validation and application in metabolic, functional, …

The relationship between serum uric acid and cognitive function in patients with chronic heart failure

W Niu, H Yang, C Lu - BMC Cardiovascular Disorders, 2020 - Springer
… study was relatively small, and future studies examining the associations between serum
UA and cognitive function in CHF patients should employ more samples to increase the validity

An early accumulation of serum uric acid confers more risk of heart failure: a 10-year prospective cohort study

X Tian, S Chen, Y Zhang, X Xia, Q Xu… - European Heart …, 2024 - academic.oup.com
… (SUA) is the end product of the purine nucleotide metabolism in human body.Apart from …
Several sensitivity analyses were further performed to validate the robustness of the findings. …

Elevated serum uric acid and self-reported heart failure in US adults: 2007–2016 national health and nutrition examination survey

ML Stone, MR Richardson, L Guevara, BG Rand… - Cardiorenal …, 2019 - karger.com
… (sUA), or urate, is the end product of purine metabolism that … the use of a large nationally
representative sample of US adults. This is important because it increases the external validity

In-hospital serum uric acid change predicts adverse outcome in patients with heart failure

H Yamamoto, Y Nagatomo, K Mahara… - … of Cardiac Failure, 2020 - Elsevier
… UA itself also affects the cardiovascular pathology through its platelet aggregation, … In patients
with heart failure (HF) hyperuricemia occurs owing to impaired oxidative metabolism 3 and …

Metabolic modulation predicts heart failure tests performance

D Contaifer Jr, LF Buckley, G Wohlford, NG Kumar… - PLoS …, 2019 - journals.plos.org
… thereby supporting the validity of our findings while at the same time characterizing the …
uric acid elevation in poor performance, and uric acid was associated with markers of metabolic

Serum uric acid and fatal myocardial infarction: detection of prognostic cut-off values: the URRAH (Uric Acid Right for Heart Health) study

E Casiglia, V Tikhonoff, A Virdis, S Masi… - Journal of …, 2020 - journals.lww.com
uric acid (SUA) and cardiovascular disease, especially … Uric acid is the final product of nucleic
acid metabolism, and its … SUA was then confirmed using internal validation, that is retesting …

Uric acid variability at midlife as an independent predictor of coronary heart disease and all-cause mortality

C Grossman, E Grossman, U Goldbourt - PLoS One, 2019 - journals.plos.org
… and long-term mortality from stroke, coronary heart disease (CHD) and all causes mortality
[15]. … If we assume that SUA is a marker of metabolic and hemodynamic changes, then we can …