Induced pluripotent stem cells: Reprogramming platforms and applications in cell replacement therapy

A Al Abbar, SC Ngai, N Nograles, SY Alhaji… - BioResearch open …, 2020 - liebertpub.com
… The generation of induced pluripotent stem cells (iPSCs) from differentiated mature … various
diseases, we highlight the successes and challenges of iPSCs in cell replacement therapy

Induced pluripotent stem cells (iPSCs)—roles in regenerative therapies, disease modelling and drug screening

MAM Aboul-Soud, AJ Alzahrani, A Mahmoud - Cells, 2021 - mdpi.com
… The advantage of using iPSCs is their ability to differentiate into any cell type, and can be
maintained indefinitely, thus becoming a potential source for cell replacement therapies. The …

Induced pluripotent stem cells and their use in human models of disease and development

P Karagiannis, K Takahashi, M Saito… - Physiological …, 2019 - journals.physiology.org
… We also hypothesized that these factors can transform differentiated somatic cells to ESC-like
cells. Using in silico subtraction, we identified expressed-sequence tags (ESTs) that were …

[HTML][HTML] Differentiating induced pluripotent stem cells into renal cells: a new approach to treat kidney diseases

P de Carvalho Ribeiro, LF Oliveira… - Stem cells …, 2020 - ncbi.nlm.nih.gov
… -RCs and their application to the kidney are discussed in this review. Furthermore, the way
differentiation protocols of induced pluripotent stem cells into renal cells may also be applied …

Induced pluripotent stem cells: hope in the treatment of diseases, including muscular dystrophies

D Gois Beghini, S Iwao Horita, CM Cascabulho… - International journal of …, 2020 - mdpi.com
… the differentiation of RNA-induced pluripotent stem cells (RiPSCs) into terminally differentiated
myogenic cells [35]. … transcribed mRNAs triggered somatic cell reprogramming with higher …

Pluripotent and multipotent stem cells and current therapeutic applications

MG Worku - Stem Cells and Cloning: Advances and Applications, 2021 - Taylor & Francis
… Adult stem cells are responsible for replacing differentiated cellspluripotent stem cells
(iPSCs) are commonly used in diseasepluripotent stem cells have a wide range of uses in gene …

Patient and disease–specific induced pluripotent stem cells for discovery of personalized cardiovascular drugs and therapeutics

DT Paik, M Chandy, JC Wu - Pharmacological reviews, 2020 - ASPET
… Klf4) can induce reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) has
… is used to promote differentiation of iPSCs to mesodermal lineage, followed by a treatment

Advances in pluripotent stem cells: history, mechanisms, technologies, and applications

G Liu, BT David, M Trawczynski, RG Fessler - Stem cell reviews and …, 2020 - Springer
… and differentiation of pluripotent stem cells (PSCs), next moving to the maintenance of stem
cells … In addition, VSELs may overcome several problems of ESCs (ethical controversies) and …

Differentiation of human induced pluripotent stem cells into erythroid cells

M Ebrahimi, M Forouzesh, S Raoufi, M Ramazii… - Stem Cell Research & …, 2020 - Springer
… state has been suggested as an alternative source and a novel opportunity for patient-specific
stem cell-based therapies, modeling of RBCs diseases, and drug testing [155]. Previous …

Human pluripotent stem cells-based therapies for neurodegenerative diseases: current status and challenges

E Ford, J Pearlman, T Ruan, J Manion, M Waller… - Cells, 2020 - mdpi.com
Pluripotent stem cells are capable of differentiating into the multitude of … the major focus
of cell replacement therapies for the treatment of neurological disorders. Human embryonic …