The place of ARBs in heart failure therapy: is aldosterone suppression the key?

U Markan, S Pasupuleti, CM Pollard… - … in Cardiovascular …, 2019 - journals.sagepub.com
… (and valsartan) over most other ARBs currently in clinical use. … HFrEF) patients on top of their
standard treatment. Importantly… provide clinical benefits that valsartan (Diovan) alone cannot…

Patient Selection Is the Key to EMPACTing Development of Heart Failure After Myocardial Infarction

A Kochar, R Gattani, M Vaduganathan - Journal of the American College of …, 2024 - jacc.org
Post myocardial infarction (MI) heart failure (HF) remains highly prevalent … use of SGLT2i
in post-MI care. However, examining secondary endpoints in EMPACT-MI, empagliflozin use

[HTML][HTML] High-quality Valsartans Contributing to the Treatment of Hypertension and Beyond for More than 15 Years

G Marinšek, A Glavač Povhe, D Milovanovič Jarh… - Cardiologia …, 2022 - hrcak.srce.hr
Valsartan is an angiotensin receptor antagonist used for the treatment of hypertension, heart
failure, and post-myocardial … (HF) and post-myocardial infarction (MI) in order to reduce …

Doprinos visokokvalitetnih valsartana liječenju arterijske hipertenzije i drugih bolesti već više od 15 godina

G Marinšek, A Glavač Povhe, D Milovanovič Jarh… - Cardiologia …, 2022 - hrcak.srce.hr
Valsartan is an angiotensin receptor antagonist used for the treatment of hypertension, heart
failure, and post-myocardial … (HF) and post-myocardial infarction (MI) in order to reduce …

Effect of sacubitril/valsartan on biomarkers of extracellular matrix regulation in patients with HFpEF

JW Cunningham, BL Claggett, E O'Meara… - Journal of the American …, 2020 - jacc.org
heart failure with preserved ejection fraction. Given the biochemical targets of sacubitril/valsartan
beta-blocker use at baseline. Within the biomarker substudy, baseline characteristics of …

Sacubitril/valsartan ameliorates cardiac function and ventricular remodeling in CHF rats via the inhibition of the tryptophan/kynurenine metabolism and inflammation

J Gan, Y Wang, Y Deng, J Zhang, S Wang, X Jiang… - Scientific Reports, 2024 - nature.com
… The rat model of post-myocardial infarction CHF was induced by left anterior descending (…
Sacubitril/valsartan is a widely used medication for the treatment of heart failure and is …

The effects of angiotensin receptor-neprilysin inhibition on major coronary events in patients with acute myocardial infarction: insights from the PARADISE-MI trial

R Mehran, PG Steg, MA Pfeffer, K Jering, B Claggett… - Circulation, 2022 - Am Heart Assoc
… /valsartan on coronary outcomes in patients with AMI. … labeling for sacubitril/valsartan for
use in patients with chronic HF … heart disease, we conducted a sensitivity analysis substituting …

Clinical outcomes in patients with acute decompensated heart failure randomly assigned to sacubitril/valsartan or enalapril in the PIONEER-HF trial

DA Morrow, EJ Velazquez, AD DeVore, AS Desai… - Circulation, 2019 - Am Heart Assoc
… inhibitor sacubitril/valsartan reduces the rate of cardiovascular death or … the use of
sacubitril/valsartan to treat patients with … of sacubitril/valsartan among patients hospitalized for …

Is Sacubitril/Valsartan a Superior Agent in Heart Failure With Reduced Ejection Fraction? A Review of Randomized Comparative Trials

JP Rindone, CK Mellen, M Goldenstein - Hospital Pharmacy, 2024 - journals.sagepub.com
… results among randomized trials was the comparator used versus SV. In the PARADIGM HF,
… who were post myocardial infarction or those that required hospitalization for heart failure (…

Sacubitril/valsartan and arrhythmic burden in patients with heart failure and reduced ejection fraction: A systematic review and meta-analysis

A Pozzi, R Abete, E Tavano, SL Kristensen, F Rea… - Heart Failure …, 2023 - Springer
… among patients … of ventricular arrhythmias with sacubitril/valsartan treatment. Compared
to Wang et al. and Mujadzic et al., we specifically focused our topic in chronic HFrEF patients. …