Clinical and immunological effects of p53-targeting vaccines
… include p53 peptides, viral vectors, and dendritic cells pulsed … Under cellular stress, p53
becomes activated and stabilized to … p53- and PADRE-peptide–pulsed autologous DCs. Before …
becomes activated and stabilized to … p53- and PADRE-peptide–pulsed autologous DCs. Before …
Personalized neoantigen pulsed dendritic cell vaccine for advanced lung cancer
Z Ding, Q Li, R Zhang, L Xie, Y Shu, S Gao… - Signal transduction and …, 2021 - nature.com
… neoantigen peptide-pulsed autologous DC vaccine and … The number of mutations in the
TP53 gene ranks at the top, … Eventually, the Neo-DCVac stabilized the patient’s condition …
TP53 gene ranks at the top, … Eventually, the Neo-DCVac stabilized the patient’s condition …
Trial watch: dendritic cell vaccination for cancer immunotherapy
J Sprooten, J Ceusters, A Coosemans… - …, 2019 - Taylor & Francis
… targets for the development of anticancer vaccines. DC-based anticancer vaccination relies
on patient-derived DCs pulsed with a source of tumor-associated antigens (TAAs) in the …
on patient-derived DCs pulsed with a source of tumor-associated antigens (TAAs) in the …
Alpha-type-1 polarized dendritic cell-based vaccination in newly diagnosed high-grade glioma: a phase II clinical trial
K Mitsuya, Y Akiyama, A Iizuka, H Miyata… - Anticancer …, 2020 - ar.iiarjournals.org
… vaccines were continued until progressive disease (PD) was determined by immune-related
(… of HLA-A2 or A24 peptide-pulsed α-type-1 polarizing DC vaccines for the treatment of high-…
(… of HLA-A2 or A24 peptide-pulsed α-type-1 polarizing DC vaccines for the treatment of high-…
Promising new tools for targeting p53 mutant cancers: Humoral and cell-based immunotherapies
V Chasov, M Zaripov, R Mirgayazova… - Frontiers in …, 2021 - frontiersin.org
… involves the use of tumor vaccines made from autologous or … to electroporate immature
dendritic cells for subsequent co-… disulfide bridge for improved stabilization. When compared to …
dendritic cells for subsequent co-… disulfide bridge for improved stabilization. When compared to …
Dendritic cell vaccines in ovarian cancer
X Zhang, T He, Y Li, L Chen, H Liu, Y Wu… - Frontiers in …, 2021 - frontiersin.org
… II trial of the p53 peptide cancer vaccine and DC vaccine (16)… response (PR), disease
stabilization, and prolonged survival … -associated antigens used to load dendritic cell vaccines. …
stabilization, and prolonged survival … -associated antigens used to load dendritic cell vaccines. …
Development of peptide‐based vaccines for cancer
N Abd-Aziz, CL Poh - Journal of oncology, 2022 - Wiley Online Library
… modulate dendritic cell homeostasis [121, 122]. A phase I clinical trial of RNF43 peptide-pulsed …
The combination showed reduced tumor burden and long-term disease stability without …
The combination showed reduced tumor burden and long-term disease stability without …
Therapeutic cancer vaccination with ex vivo RNA-transfected dendritic cells—an update
J Dörrie, N Schaft, G Schuler, B Schuler-Thurner - Pharmaceutics, 2020 - mdpi.com
… new ones) and stabilization of disease were usually reported in … dendritic cell injection
sites, flu-like symptoms (fever, chills, headache, and myalgia) and fatigue. These immune-related …
sites, flu-like symptoms (fever, chills, headache, and myalgia) and fatigue. These immune-related …
Pharmacological combination of nivolumab with dendritic cell vaccines in cancer immunotherapy: an overview
J Calmeiro, MA Carrascal, AR Tavares… - Pharmacological …, 2021 - Elsevier
… T cell therapy with Nivolumab and NY-ESO-1 peptide-pulsed … p53-DC) used in this study is
obtained by the insertion of the … and CD8 + T cells, leading to disease stabilization in most of …
obtained by the insertion of the … and CD8 + T cells, leading to disease stabilization in most of …
Development of Cell Technologies Based on Dendritic Cells for Immunotherapy of Oncological Diseases
V Kurilin, A Alshevskaya, S Sennikov - Biomedicines, 2024 - mdpi.com
… Immunotherapy using dendritic cell-based vaccination is a natural approach using the …
outcomes and address the challenges associated with dendritic cell vaccination. Neoantigens are …
outcomes and address the challenges associated with dendritic cell vaccination. Neoantigens are …