[HTML][HTML] Investigating a Plasmodium falciparum erythrocyte invasion phenotype switch at the whole transcriptome level

PB Nyarko, SJ Tarr, Y Aniweh, LB Stewart… - Scientific reports, 2020 - nature.com
… and immune evasion. Overcoming the challenge posed by … to be associated with different
invasion pathways. To this end, we … changes that mediate phenotypic variation will be the focus …

[HTML][HTML] Parasite-Related Genetic and Epigenetic Aspects and Host Factors Influencing Plasmodium falciparum Invasion of Erythrocytes

M Ararat-Sarria, MA Patarroyo… - Frontiers in cellular and …, 2019 - frontiersin.org
… target cell invasion, thereby conferring mechanisms for evading a … erythrocyte receptor profile);
however, they may change the … autophagy pathway and Pf HP1/H3K9me3-mediated gene …

[HTML][HTML] P. falciparum Invasion and Erythrocyte Aging

MF Alves-Rosa, NM Tayler, D Dorta, LM Coronado… - Cells, 2024 - mdpi.com
… to enzymatic treatment, two main invasion pathways for P. … erythrocytes against complement
or phagocytosis-mediatedinvasion receptors change over the lifespan of the RBC? …

Transcriptome analysis reveals molecular targets of erythrocyte invasion phenotype diversity in natural Plasmodium falciparum isolates from Cameroon

IA Ngoh, K Mane, J Manneh, F Bojang… - Frontiers in …, 2024 - frontiersin.org
variation associated with the use of alternative RBC invasion … relevance to RBC surface
remodeling and immune evasion in … bind RBC receptors but mediate later steps of invasion and …

Plasmodium falciparum exploits CD44 as a coreceptor for erythrocyte invasion

B Baro, CY Kim, C Lin, AK Kongsomboonvech… - Blood, 2023 - ashpublications.org
… We identified 50 spots with ≥1.3-fold change in intensity in 1 or … EBA-175 to mediate invasion
in certain strain backgrounds … of CD44related pathways as targets for malaria intervention. …

[HTML][HTML] Getting in: The structural biology of malaria invasion

H Kumar, NH Tolia - PLoS pathogens, 2019 - journals.plos.org
… malaria in humans, Plasmodium falciparum (Pf) and P. vivax (Pv) … are highly polymorphic,
and this variation will have to be … evasion from neutralizing antibodies that target the invasion

[HTML][HTML] Mechanisms for Host Immune Evasion Mediated by Plasmodium falciparum-Infected Erythrocyte Surface Antigens

A Sakoguchi, H Arase - Frontiers in Immunology, 2022 - frontiersin.org
… This phenomenon is termed ‘antigenic variation’ and it allows P. falciparum to evade the
host immune … Figure 2 The signaling pathways mediated by inhibitory immune receptors. The …

Identification of Potential Drug Targets in Erythrocyte Invasion Pathway of Plasmodium falciparum

MM Kazan, MM Asmare, RK Mahapatra - Current Microbiology, 2023 - Springer
Invasion of erythrocytes by Plasmodium merozoites is a complex multi-step process that
is mediated … and parasite ligands [8] which varies according to genetic background of the …

[HTML][HTML] Hotspots in Plasmodium and RBC Receptor-Ligand Interactions: Key Pieces for Inhibiting Malarial Parasite Invasion

MA Patarroyo, J Molina-Franky, M Gómez… - International Journal of …, 2020 - mdpi.com
… some Plasmodium falciparum and Plasmodium vivax … of the main immune response
evasion mechanisms), several … vivax have multiple, complex RBC invasion routes mediated by …

Plasmodium vivax Strains Use Alternative Pathways for Invasion

U Kanjee, C Grüring, P Babar, A Meyers… - The Journal of …, 2021 - academic.oup.com
Variation in invasion pathway usage has been observed in the often lethal Plasmodium
falciparum … of immune evasion and cellular age tropism, as well as P. vivax pathogenesis. …