The role of sema4D in vasculogenic mimicry formation in non‐small cell lung cancer and the underlying mechanisms

Y Xia, XY Cai, JQ Fan, LL Zhang… - … journal of cancer, 2019 - Wiley Online Library
… -small cell lung cancers (NSCLCs). Vasculogenic mimicry (VM), the formation of vascular
networks composed of aggressive cancer cells, may be one of the reasons. our study explored …

[HTML][HTML] Thrombin is a therapeutic target for non-small-cell lung cancer to inhibit vasculogenic mimicry formation

B Zhao, M Wu, Z Hu, Y Ma, W Qi, Y Zhang… - Signal transduction and …, 2020 - nature.com
Tumor cells transform into endothelial cells by epithelial-to-mesenchymal transition, which
is characterized by vasculogenic mimicry (VM). VM not only accelerates tumor progression …

[HTML][HTML] Vasculogenic mimicry in carcinogenesis and clinical applications

Q Luo, J Wang, W Zhao, Z Peng, X Liu, B Li… - Journal of hematology & …, 2020 - Springer
… Prevalent circulating tumor cells (CTCs) is one of the characteristic of small cell lung cancer
(… kinase induces VM formation in non-small-cell lung cancer by activating of the FAK and AKT …

[HTML][HTML] HIF-1α promoted vasculogenic mimicry formation in lung adenocarcinoma through NRP1 upregulation in the hypoxic tumor microenvironment

R Fu, W Du, Z Ding, Y Wang, Y Li, J Zhu, Y Zeng… - Cell death & …, 2021 - nature.com
tumor metastasis, and vasculogenic mimicry (VM) is an important form of neovascularization
found in highly invasive tumors, including lung cancer. … Non-small cell lung cancer (NSCLC) …

[HTML][HTML] Vasculogenic mimicry: become an endothelial cell “but not so much”

M Fernández-Cortés, D Delgado-Bellido… - Frontiers in …, 2019 - frontiersin.org
Vasculogenic mimicry refers to the ability of cancer cells to organize themselves into
vascular-like structures for the obtention of nutrients and oxygen independently of normal blood …

[HTML][HTML] Regulation networks driving vasculogenic mimicry in solid tumors

ON Hernández de la Cruz, JS López-González… - Frontiers in …, 2020 - frontiersin.org
… In lung cancer, the estrogen receptor β interacts with different estrogen response elements …
145-5p and linked to non-small cell lung cancer metastasis). This promotes VM formation and …

[HTML][HTML] Mechanisms of vasculogenic mimicry in hypoxic tumor microenvironments

X Wei, Y Chen, X Jiang, M Peng, Y Liu, Y Mo, D Ren… - Molecular cancer, 2021 - Springer
… or HIF molecules promote the VM process in multiple tumor types including cervical cancer
[13], small cell lung cancer [14], liver cancer [15], and gallbladder cancer [16]. HIF-1 can also …

[HTML][HTML] Molecular mechanisms and anticancer therapeutic strategies in vasculogenic mimicry

X Zhang, J Zhang, H Zhou, G Fan, Q Li - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
… A recent study reported that VE-cadherin-positive small cell lung cancer (SCLC) cells
were able to show VM and were more resistant to cisplatin than VE-cadherin negative …

Vasculogenic mimicry, a complex and devious process favoring tumorigenesis–interest in making it a therapeutic target

L Treps, S Faure, N Clere - Pharmacology & therapeutics, 2021 - Elsevier
… non-small cell lung cancer … The two types of vascular mimicry. A) Patterned vasculogenic
mimicry (VM) forms architectural patterns of loops and networks as revealed by periodic acid-…

Estrogen receptor β promotes the vasculogenic mimicry (VM) and cell invasion via altering the lncRNA-MALAT1/miR-145-5p/NEDD9 signals in lung cancer

W Yu, J Ding, M He, Y Chen, R Wang, Z Han, EZ Xing… - Oncogene, 2019 - nature.com
… the progression of non-small cell lung cancer (NSCLC), its linkage to alteration of the
vasculogenic mimicry (VM) formation to influence the NSCLC cell invasion remains unclear. Here, …