… hormonal therapy over hormonal treatment alone in IS. We describe three patients with IS who
developed acute encephalopathy with extrapyramidal symptoms, vigabatrin-… -month ICISS …

… Multicenter study ICISS (International collaborative Infantile spasm study) showed that a …
therapy of hormone plus vigabatrin and single therapy of hormone in treatment of infantile …

… , when compared with hormone therapy (either ACTH or high-dose … treatment. For this
reason, we sought to standardize the use of hormone therapy over vigabatrin as the first treatment …

… Vigabatrin with hormonal treatment versus hormonal treatment alone ( ICISS ) for infantile
spasms : 18-month outcomes of an open-label , randomised controlled trial. :715–25. 25. …

… step alone, … therapy with hormone therapy and vigabatrin, if the ICISS trial shows that it
confers long-term developmental benefits over a sequential pathway commencing with hormone …

… and vigabatrin over oral steroids alone but confirmation in real-life conditions is mandatory.
… evidence for adrenocorticotropic hormone (ACTH), prednisolone, and vigabatrin (VGB) [7]. …

… of electrographic infantile spasms, treatment with cosyntropin alone was successful in 9/12
(… the first treatment for infantile spasms syndrome should be hormone therapy, with vigabatrin …

… treatment of infantile spasms in 2009 [7]. In the United Kingdom Infantile Spasms Study (UKISS)
trial, hormonal … response to combination therapy than to vigabatrin alone. Further study …

… ICISS trial published its results in 2017 and revealed that hormonal treatment with concomitant
vigabatrin … one ratio to either hormonal therapy with vigabatrin or hormonal therapy alone. …

… therapy of prednisolone and vigabatrin was more effective than prednisolone alone in children
having infantile … enhanced when hormone therapy was paired with vigabatrin. The four-…