Vimentin intermediate filaments as potential target for cancer treatment
K Strouhalova, M Přechová, A Gandalovičová… - Cancers, 2020 - mdpi.com
… anticancer therapies. However, medicinal chemistry modifications of the FiVe1 compound or
a discovery of similar vimentin-targeting drug … potential of vimentin targeting as a therapy for …
a discovery of similar vimentin-targeting drug … potential of vimentin targeting as a therapy for …
Vimentin as a multifaceted player and potential therapeutic target in viral infections
… evidence on vimentin involvement in infection and associated damage and hypothesize
about its potential interest as an additional therapeutic target against certain viral infections. …
about its potential interest as an additional therapeutic target against certain viral infections. …
Vimentin is at the heart of epithelial mesenchymal transition (EMT) mediated metastasis
S Usman, NH Waseem, TKN Nguyen, S Mohsin… - Cancers, 2021 - mdpi.com
… Several missense and frameshift mutations reported in vimentin in human cancers may also
… vimentin should be a therapeutic target using molecular technologies that will curb cancer …
… vimentin should be a therapeutic target using molecular technologies that will curb cancer …
Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy
JR van Beijnum, EJM Huijbers, K van Loon… - Nature …, 2022 - nature.com
… tumor cell lines 19 . However, we observed cancer stage-related presence of extracellular
vimentin in the secretome of human colorectal tumors, while total, intracellular vimentin levels …
vimentin in the secretome of human colorectal tumors, while total, intracellular vimentin levels …
Vimentin: Regulation and pathogenesis
… cell growth, cell differentiation, cancer, epithelial to mesenchymal transition and viral … of
vimentin, its presence at the cell surface, the role of extracellular vimentin as a specific marker, its …
vimentin, its presence at the cell surface, the role of extracellular vimentin as a specific marker, its …
Vimentin as a target for the treatment of COVID-19
Z Li, D Paulin, P Lacolley… - BMJ open …, 2020 - bmjopenrespres.bmj.com
… in which we propose vimentin as a potential therapeutic target against viral infection, …
Vimentin was also been previously proposed as a potential therapeutic target in cancer treatment …
Vimentin was also been previously proposed as a potential therapeutic target in cancer treatment …
Identification of miR-515-3p and its targets, vimentin and MMP3, as a key regulatory mechanism in esophageal cancer metastasis: functional and clinical significance
HF Hu, WW Xu, WX Zhang, X Yan, YJ Li, B Li… - … and targeted therapy, 2020 - nature.com
… cancer progression including invasion and metastasis. Here, we revealed for the first time that
vimentin and MMP3 are target … of miR-515-3p in cancer is unknown up to now. We verified …
vimentin and MMP3 are target … of miR-515-3p in cancer is unknown up to now. We verified …
Vimentin activation in early apoptotic cancer cells errands survival pathways during DNA damage inducer CPT treatment in colon carcinoma model
S Chakraborty, A Kumar, MM Faheem, A Katoch… - Cell Death & …, 2019 - nature.com
… Since, NFκB expression was downmodulated in CPT plus si-Vimentin condition, we
hypothesized that Vimentin could have a role in controlling NFκB transcription at its promoter level. …
hypothesized that Vimentin could have a role in controlling NFκB transcription at its promoter level. …
The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells
CH Kaschula, R Tuveri, E Ngarande, K Dzobo… - BMC cancer, 2019 - Springer
… of its cellular protein targets. In this study we identify vimentin as a target that undergoes
thiolysis exchange with ajoene in cancer cells. We show that the covalent modification of …
thiolysis exchange with ajoene in cancer cells. We show that the covalent modification of …
Vimentin as a potential target for diverse nervous system diseases
KZ Chen, SX Liu, YW Li, T He, J Zhao… - Neural regeneration …, 2023 - journals.lww.com
… an overview of vimentin in spinal cord injury, … potential therapeutic methods involving vimentin
manipulation in improving axonal regeneration, alleviating infection, inhibiting brain tumor …
manipulation in improving axonal regeneration, alleviating infection, inhibiting brain tumor …