The role of memory CD8+ T cells in vitiligo

RL Riding, JE Harris - The Journal of Immunology, 2019 - journals.aai.org
Expression of CXCR3 on melanocyte-specific CD8 + T cells in vitiligo is required for skin
tissue homing because CXCR3-… Vitiligo skin is imprinted with resident memory CD8 T cells

Emerging role of tissue resident memory T cells in vitiligo: from pathogenesis to therapeutics

F Shah, S Patel, R Begum, M Dwivedi - Autoimmunity Reviews, 2021 - Elsevier
… frequency of skin CD69 + CD103 + CD8 + TRM cells in vitiligo patients … expression of CXCR3
(a homing receptor of TRM) within the perilesional skin of patients with progressive vitiligo […

Pathophysiology of skin resident memory T cells

…, K Kurihara, T Fujiyama, T Honda - Frontiers in …, 2021 - frontiersin.org
cells express CXCR3 in vitiligo, indicating inclusion of the … -homing molecules are imprinted
during T cell priming (89). … Tissue-resident memory CD8+ T cells continuously patrol skin

Tissue-resident memory T cells in skin diseases: a systematic review

T Emmanuel, J Mistegård, A Bregnhøj… - International Journal of …, 2021 - mdpi.com
… been characterized in various skin diseases including psoriasis, vitiligo and cutaneous T-…
memory CD8 + T cells following infection. However, the role of CD4 and CD8 expression has …

Resident memory T cells

H Akbaba - Cells of the Immune System, 2020 - books.google.com
… and chemokine receptors including CXCR3 and CCR6, and … Vitiligo lesions recur in the
same areas of the skin and this is a … Vitiligo skin is imprinted with resident memory CD8 T cells

Tissue-resident memory T cells in the skin

S Khalil, T Bardawil, M Kurban, O Abbas - Inflammation Research, 2020 - Springer
… the formation of memory CD8+ T cells in secondary lymphoid … , circulating CD8+ T cells
lose the expression of homing … , circulating CXCR3+ CD8+ T RCM cells in vitiligo patients …

[HTML][HTML] Resident memory and recirculating memory T cells cooperate to maintain disease in a mouse model of vitiligo

JM Richmond, JP Strassner, M Rashighi… - Journal of Investigative …, 2019 - Elsevier
… characterization of skin memory T cells in vitiligo, demonstrate … in the skin where autoantigen
is expressed during vitiligo. … ," which covers targeting CXCR3 for the treatment of vitiligo. …

Phenotype and function of circulating memory T cells in human vitiligo

…, C Jacquemin, T Barnetche… - British Journal of …, 2020 - academic.oup.com
… the recruitment of T cells expressing their cognate receptor CXCR3.7 In … vitiligo perilesional
skin is imprinted with CD8 + T cells expressing CXCR3, characterized by a resident memory

Protective and pathogenic roles of resident memory T cells in human skin disorders

R Watanabe - Journal of Dermatological Science, 2019 - Elsevier
… Recent studies demonstrated that both stable and active vitiligo perilesional skin is enriched
with IFNγ- and TNFα-producing CD8 T RM with expression of CD69, CD103, and CXCR3, …

Resident memory T cells in autoimmune skin diseases

GE Ryan, JE Harris, JM Richmond - Frontiers in immunology, 2021 - frontiersin.org
… in autoimmune skin conditions, specifically vitiligo, psoriasis, … induce NKG2D expression on
effector memory CD8+ T cells (57… ” which covers targeting CXCR3 for the treatment of vitiligo. …