A rare syndrome mimicking scleroderma: Werner syndrome

B Okyar, S Akben, B Torun… - Modern Rheumatology …, 2023 - academic.oup.com
… to systemic sclerosis may be seen. Therefore, it may mimic this disease as misleading. A
43-year-old female patient was admitted to our clinic with a pre-diagnosis of systemic sclerosis

[HTML][HTML] Werner syndrome in two case reports: The wild and the tame systemic sclerosis mimics

H El-Gendy, KS Shohdy, W Rashad… - The Egyptian …, 2019 - Elsevier
… This close mimic with systemic sclerosis might mask cases of Werner syndrome in … The
cases are illustrative for the confusion that may arise with systemic sclerosis and the difficulty in …

Adult progeria: a new mutation in the WRN gene

ML Rocha, AT Chicharo, G Sequeira… - BMJ Case Reports …, 2022 - casereports.bmj.com
Werner syndrome (WS) is a rare autosomal recessive inherited progeroid … Scleroderma-like
pattern can also be present in WS nailfold capillaroscopy as recently reported.21 A clinical …

Dynamics of oligodendrocyte generation in multiple sclerosis

MSY Yeung, M Djelloul, E Steiner, S Bernard… - Nature, 2019 - nature.com
Shadow plaques are focal multiple sclerosis lesions in which the inflammation has subsided…
of multiple sclerosis results in shadow plaques, and in patients with multiple sclerosis these …

[HTML][HTML] A case of Myhre syndrome mimicking juvenile scleroderma

B Jensen, R James, Y Hong, E Omoyinmi… - Pediatric …, 2020 - Springer
… of scleroderma, and highlight the molecular pathways that can lead to pathological fibrosis.
This may provide clues to the pathogenesis of sporadic juvenile scleroderma, and could

[HTML][HTML] Oligodendrocyte generation dynamics in multiple sclerosis

MSY Yeung, M Djelloul, E Steiner, S Bernard… - Nature, 2019 - ncbi.nlm.nih.gov
… oligodendrocytes from shadow plaques. Shadow plaques are focal multiple sclerosis lesions
… models of multiple sclerosis results in shadow plaques, and shadow plaques in multiple …

Chronic demyelination and axonal degeneration in multiple sclerosis: pathogenesis and therapeutic implications

TJ Simkins, GJ Duncan, D Bourdette - Current neurology and …, 2021 - Springer
… Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous
system (CNS). Inflammatory attacks in MS lead to both demyelination and axonal damage. …

[HTML][HTML] Revisiting the pathoetiology of multiple sclerosis: has the tail been wagging the mouse?

MK Sen, MSM Almuslehi, PJ Shortland… - Frontiers in …, 2020 - frontiersin.org
… These lesions were accompanied by atrophy and discolouration that were termed “a peculiar
disease,” (1) but made no attribution to Multiple Sclerosis (MS). Twenty-eight years later, in …

[HTML][HTML] New epidermal-growth-factor-related insights into the pathogenesis of multiple sclerosis: is it also epistemology?

G Scalabrino - Frontiers in neurology, 2021 - frontiersin.org
sclerosis (MS) because subacute combined degeneration is still considered in the differential
diagnosis of early MS (6–8); and some cases of late-onset CblC disease [a … levels is lost in …

[HTML][HTML] Alterations of oligodendrocyte and myelin energy metabolism in multiple sclerosis

E López-Muguruza, C Matute - International Journal of Molecular …, 2023 - mdpi.com
… -relapsing MS may undergo transient energy deficits compromising their function (signal
transmission) and structure. Partial remyelination in shadow plaques may restore energy supply …