[HTML][HTML] Head and neck squamous cell carcinoma
DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
… that HPV-positive HNSCC could be prevented by successful vaccination campaigns worldwide…
HNSCC of the oral cavity is generally treated with surgical resection, followed by adjuvant …
HNSCC of the oral cavity is generally treated with surgical resection, followed by adjuvant …
The complex molecular genetics of familial hypercholesterolaemia
AJ Berberich, RA Hegele - Nature Reviews Cardiology, 2019 - nature.com
… transfer protein, or PSCK9; and gene therapy) can trace their development to the need to …
FH to prevent the early onset of cardiovascular disease (CVD) 2 . However, despite being an …
FH to prevent the early onset of cardiovascular disease (CVD) 2 . However, despite being an …
Precision medicine in diabetes: a consensus report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
… Identifying predictive markers (especially genetic markers) of serious adverse events in
patients treated with these drugs presents an additional area urgently in need of greater attention…
patients treated with these drugs presents an additional area urgently in need of greater attention…
[HTML][HTML] Return of individual genomic research results: are laws and policies keeping step?
A Thorogood, G Dalpé, BM Knoppers - … Journal of Human Genetics, 2019 - nature.com
… economic or psychological harm, such as genetic discrimination. Numerous national laws
[24;… ’s genetic information law authorises the disclosure of individual results that may prevent “…
[24;… ’s genetic information law authorises the disclosure of individual results that may prevent “…
You are what you eat: diet, health and the gut microbiota
… During food shortage, bacteria can switch between energy sources by employing sensing
and regulatory mechanisms controlling gene expression. Taxa that can readily adjust to …
and regulatory mechanisms controlling gene expression. Taxa that can readily adjust to …
[HTML][HTML] Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites
A Promonet, I Padioleau, Y Liu, L Sanz… - Nature …, 2020 - nature.com
… arrest at TTS is an active process that prevents collisions between RNA and DNA polymerases,
as previously reported in budding yeast 58,59 . Transient fork pausing could help cells …
as previously reported in budding yeast 58,59 . Transient fork pausing could help cells …
[HTML][HTML] High-fat diet promotes colorectal tumorigenesis through modulating gut microbiota and metabolites
… Moreover, we treated patient-derived CRC organoids with NDGA and nervonic acid respectively
and found that both NDGA and nervonic acid could significantly inhibit CRC organoids …
and found that both NDGA and nervonic acid could significantly inhibit CRC organoids …
[HTML][HTML] A narrative review of stigma related to infectious disease outbreaks: what can be learned in the face of the Covid-19 pandemic?
… Reports of people with Asian phenotype who have been victims of racist attacks on several
occasions is proof of stigma and discrimination that could have been avoided (32, 33). …
occasions is proof of stigma and discrimination that could have been avoided (32, 33). …
An evaluation (and vindication?) of Lewis Terman: What the father of gifted education can teach the 21st century
RT Warne - Gifted Child Quarterly, 2019 - journals.sagepub.com
… This article explores the most common criticisms of Terman’s legacy: an overemphasis
on IQ, support for the meritocracy, and emphasizing genetic explanations for the origin of …
on IQ, support for the meritocracy, and emphasizing genetic explanations for the origin of …
Rational combinations of targeted cancer therapies: background, advances and challenges
H Jin, L Wang, R Bernards - Nature Reviews Drug Discovery, 2023 - nature.com
… Over the past two decades, elucidation of the genetic defects that underlie cancer has resulted
in a plethora of novel targeted cancer drugs. Although these agents can initially be highly …
in a plethora of novel targeted cancer drugs. Although these agents can initially be highly …